The action of an active principle from apocynum / by H.H. Dale and P.P. Laidlaw.

  • Henry Hallett Dale
Date:
[1909?]
Catalogue details

Licence: Public Domain Mark

Credit: The action of an active principle from apocynum / by H.H. Dale and P.P. Laidlaw. Source: Wellcome Collection.

    23/34
    the spontaneous rhythm. Contraction of the spleen was shown in plethys- mographic records, and in one case wide, rhythmic variations of volume appeared, quite independent of the blood pressure. Intense tonic con¬ traction of the urinary bladder is caused by intravenous injections, and, after Fig. 12. x ^ linear. Isolated loop of rabbit’s jejunum. Downstroko of lever = contraction. At ^ 1 mg. Apocynamarin added to the 250 cc. of warm oxygenated Ringer’s solution in which the loop was suspended. At change to pure Ringer. Fig. 13. X 1 linear. Isolated horn of cat’s uterus (non-pregnant). Conditions as in Fig. 12. ,'namarm ; at I change to pure Ringer. a large intravenous injection, the lumen was practically obliterated. The effect on the peripheral arteries is, therefore, merely one instance of the general stimulation of plain muscle fibres.
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