A contribution to the pathology of the blood : being an account of certain crystalline changes occurring in the haemoglobin after withdrawal from the body, in the subjects of certain diseases, especially those of septic origin / by C.J. Bond.

  • Charles John Bond
Date:
[1887]
Catalogue details

Licence: Public Domain Mark

Credit: A contribution to the pathology of the blood : being an account of certain crystalline changes occurring in the haemoglobin after withdrawal from the body, in the subjects of certain diseases, especially those of septic origin / by C.J. Bond. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    evolved and circulating during the first attack have so acted on and changed the blood and tissues as to render them proof against further invasion by the same organisms— then, judging from the foregoing observations, it would appear that it is not the absorption and circulation of the highly differentiated protective product which produces in the blood this crystalline change, for it is absent in scarlet fever, measles, &c.; but that the less differentiated non-pro- tective, simple product of putrefaction does so to a marked extent, as in saprsemia, <fcc., and this points to a marked difference in the products produced by the life and growth of different organisms. We have now to consider the condition of the blood in those diseases, or rather aggregation of symptoms, associated with the presence in the blood or tissues of substances or chemical products not owing their origin to the life- history of micro-organisms. These conditions fall into two divisions: one in which the substance or poison is intro- duced from outside, as in the case of a patient saturated with ether; and another, in which the poison is produced in the body by disturbed or perverted metabolism and nutri- tion, as in the case of jaundice or uraemia. Now, as, indeed, we should expect from previous considerations, we find that, taken as a whole, the crystalline tendency is absent in all these cases. Thus, in the first division, it is absent in the blood of patients who have been long under the influence of ether or chloroform. As a rule, it is absent in cases of opium poisoning. In one fatal case, however, slight crystallisation appeared after the blood had remained on the slide for forty- eight hours, and in this case the man had been in a state of complete coma or semi-asphyxia for twelve hours previously. The second division will next be considered. Rheumatic Fever.—The crystalline tendency is absent even in well-marked cases, with a temperature of from 101° to 104°. In one case of hyperpyrexia, however, in a syphilitic subject, in which the temperature rapidly rose from 99°
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