Bacteriological and clinical studies of the diarrheal diseases of infancy with reference to the Bacillus dysenteriae (Shiga) : from the Rockefeller Institute for Medical Research / edited by Simon Flexner and L. Emmett Holt.
- Date:
- 1904
Licence: Public Domain Mark
Credit: Bacteriological and clinical studies of the diarrheal diseases of infancy with reference to the Bacillus dysenteriae (Shiga) : from the Rockefeller Institute for Medical Research / edited by Simon Flexner and L. Emmett Holt. Source: Wellcome Collection.
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![REPORT OF SEVEN CASES OF INTESTINAL INFECTION WITH THE BACILLUS DYSENTERIAE (SHIGA) OC- CURRING AT THE NEW YORK FOUNDLING . HOSPITAL, WHICH WERE TREATED WITH ANTIDYSENTERIC SERUM. BY ROWLAND G, FREEMAN, M3), , Attending Physician to the New York Foundling Hospital. Case I—Seven months old, admitted June 15, 1903. A poorly nourished, rachitic child, weighing only 9 lbs. He had diarrhea; the stools were green, with mucus and curds, occasionally fluid, three to five in twenty-four hours. There was no vomiting, temperature between 97.5° F. and 100.5° F. This con- dition persisted for one month. On July 17th his temperature began to rise, fluctuating between 100° F. and 105° F. The stools did not increase in number, but on July 21st began to contain blood, which soon became very abundant. The B. dysenterie was iso- lated from the stools. He was given “Harris” serum, 10 c.c., ON Six successive days. Blood continued for seven days and then disappeared. The stools were from two to five a day, and after two weeks improved very much in character, so that they were yellow, brown and formed, though still containing some mucus. Thereafter there was no rise in temperature. His weight varied but slightly for the next three months, a few ounces being gained and then lost. He eventually died of marasmus on November 6th. No autopsy was obtained. In this case there seemed to be some benefit from the use of the serum, but the child was unable to overcome his marantic condition. Case II]—A_ well-nourished child, seven months old, suddenly became ill with temperature of 103° F., rising in twenty-four hours to 104.8° F. The stools at first were brown and loose, two to four a day. The temperature then dropped to normal, and after three days the stools were normal for twenty- four hours; but a day later a relapse occurred, the stools became frequent and green, with mucus and blood, and the temperature rose to 103° F. The child thereafter lost ground rapidly and died, despite the injection of 10 cc. of “Harris” and 10 cc. of “Seward” serum. The temperature for the last three days was considerably elevated. The B. dysenterieé was found in the stools five days before death, and was also cultivated from the post-mortem scrapings of the intestinal mucosa. The autopsy showed an acute ileo-colitis with superficial necrosis and hemorrhages. Case III.—One year old. Following measles and after her temperature had become normal there occurred numerous green mucous stools, without blood; from these the B. dysenteri@ was isolated. The temperature at first was very](https://iiif.wellcomecollection.org/image/b32747573_0165.jp2/full/800%2C/0/default.jpg)
