A study of the various changes which occur in the tissues in acute diphtheritic toxaemia : more especially in reference to 'acute cardiac failure' / by Leonard S. Dudgeon.
- Leonard Dudgeon
- Date:
- 1906
Licence: In copyright
Credit: A study of the various changes which occur in the tissues in acute diphtheritic toxaemia : more especially in reference to 'acute cardiac failure' / by Leonard S. Dudgeon. Source: Wellcome Collection.
Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.
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![A STUDY OF THE YAEIOUS CHANGES WHICH OCCUR IN THE TISSUES IN ACUTE DIPH- THERITIC TOXAEMIA, MORE ESPECIALLY IN REFERENCE TO “ ACUTE CARDIAC FAILURE.” (From the Louis Jenner Clinical Laboratory, St. Thomas’s Hospital.) BY LEONARD S. DUDGEON, M.R.C.P.LOND. Bacteriologist to St. Thomas's Hospital and Joint Lecturer on Pathology in the Medical School; Director of the Louis Jenner Clinical Laboratory and of the Pathological Laboratories, St. Thomas’s Hospital. The cost of this research was defrayed through the munificence of Lady Jenner, who has established a scholar- ship in pathological research at St. Thomas’s Hospital, in memory of her son, Louis Jenner. Nothing has been more gratifying to me than to have been able to carry out this investigation in the laboratory where, at one time, I had the advantage of being an assistant to my friend, Dr. Louis Jenner. Introduction. At the suggestion of Dr. Foord Caiger, I have made an investigation of the various changes which occur in the viscera, nerves and muscles, in sixteen cases of acute diph- theritic toxaemia. A large amount of experimental work has also been done with the filtered toxins of the diphtheria bacillus. By comparing the results of the pathological investigations in the human cases with those which have been found in the inoculated animals, I have been able to form a definite idea of the changes which occur. Bristowe [5] examined the heart muscle in a case which was clinically malignant haemorrhagic diphtheria, and found](https://iiif.wellcomecollection.org/image/b22428483_0005.jp2/full/800%2C/0/default.jpg)


