Experimental inquiry into the physiological actions of theine, caffeine, guaranine, cocaine, and theobromine / by Alexander Bennett, M.D.
- Alexander Hughes Bennett
- Date:
- 1873
Licence: Public Domain Mark
Credit: Experimental inquiry into the physiological actions of theine, caffeine, guaranine, cocaine, and theobromine / by Alexander Bennett, M.D. Source: Wellcome Collection.
Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.
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![Tables showing the Result of Seventy-two Experiments with llieine^ Caffeine^ Guaranine, and Cocaine. Table I.—Experiments with Theine. 10. 11. 12. 13. Frog Frog Frog Frog Frog Frog Frog Frog Frog Frog Frog Frog Frog 14. 15. 17. I'^rog Frog liabbit General Effects. 1+1 Slight wealaiess of posterior extre- mities. Weakness of posterior extremities. Paralysis of limbs; loss of reflex action; respiration impeded. Complete paralysis of limbs; loss of reflex action; respiration impeded; cutaneous congestion. Gradual prostration; paralysis of all the muscles ; loss of reflex action ; respiration stopped; congestion of cutaneous surface, mucous mem- brane of mouth, and tongue. Femoral artery tied; same effect as in No. 5; uo difference between two legs. Complete prostration ; loss of reflex action; stoppage of respiration ; cutaneous congestion; stasis of blood in capillaries. Complete prostration; loss of reflex action; stoppage of respiration ; congestion of cutaneous surface. The same as No. 8. Same as No. 8, but more rapid. Femoral artery tied; symptoms same as No. 8, but tetanic spasms in addition; no difference between two legs. Rapid prostration, with tetanic symptoms. Upper part of spinal cord exposed during life; rapid prostration; after death, on touching anterior columns of cord, contraction of all the muscles; on touching posterior columns, no contractions; before death, muscular contractions fol- lowed irritation of the posterior columns. Lower portion of cord exposed dur- ing life; same as No. 13. Very rapid prostration and loss of rellex action, with usual effects. No effects from first grain. Slight weakness of posterior extremities from second grain. Result. Recovery Recovery Recovery Recovery Recovery Recoveiy Death Recovery Death Death Death Death Death Death Death Recovery I'ost-niortera Exanyniition. Heart still beats; conges- tion of vi.scera; muscles contract when electricity is applied; when spinal cord, nerves, or brain are irritated, muscular con tractions occur. Same as No. 7. Spinal cord exposed; anterior column irritated, contrac- tion of muscles ensue; posterior column irritated, no contractions. Same as No. 7. Same as No. 7. No differ ence between two legs when electricity is ap ])lied. Same as No. 7. Same as No. 7. Same as No. 7. Same as No. 7.](https://iiif.wellcomecollection.org/image/b21480047_0020.jp2/full/800%2C/0/default.jpg)
