An introduction to pathology and morbid anatomy / by T. Henry Green.
- Green, T. Henry (Thomas Henry), 1841-1923
- Date:
- 1889
Licence: Public Domain Mark
Credit: An introduction to pathology and morbid anatomy / by T. Henry Green. Source: Wellcome Collection.
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![find; and that but little of an organ ]ias been examined, even after loo sections have been carefully looked through. Galfky himself investigated twenty-eight cases, and in twenty-six demonstrated the presence of bacilli in parts other than the intestine—such as the mesenteric glands, spleen, liver, kidney. In the other two cases, the bacilli were found in a recently swollen solitary follicle of one; and the other died at the end of the fourth week of perforative peritonitis, and the intestines showed only healing ulcers. In one case, which Gaffky does not include in his list, although it had been diagnosed as typhoid, both during life and post-mortem, immense numbers of cocci were found in the organs, and it was impossible to distinguish the typhoid bacilli. Gaifky throws out the suggestion that there may be a disease clinically like typhoid due to invasion of the intestine by cocci. The bacilli were more numerous the earlier the case. If many are found in old cases, it is probable that a relapse has occurred. The process employed to demonstrate the bacilli was to harden pieces of fi^esh organs in alcohol, and to place sections cut from them in methylene blue for twenty-four hours. The solution is made by adding a saturated alcoholic solution of the blue to water until the latter cannot be seen through. The sections are clarified, and mounted in the ordinary way. Blue sections lose their colour rather quickly; those stained with Bismarck brown are better for preservation. It is most important that the organs should be fresh, for the bacilli are difficult to distinguish in sections from putrefactive organisms. The bacilli are thus described. (Fig. 167,5.) They are three times as long as broad, and their length equals one-third the diameter of a red blood-corpuscle. Their ends are distinctly rounded. Spores are not uncommonly seen—round, reaching right across the breadth of the rods, and lying at their ends. The typhoid bacilli are more or less actively mobile. They do not stain so intensely as other forms, and sometimes they do not stain uniformly ; round spots not extending across the rods, and therefore not spores, being left pale. The typhoid bacilli do not stain like tubercle-bacilli (p. 597).](https://iiif.wellcomecollection.org/image/b20390701_0588.jp2/full/800%2C/0/default.jpg)
