On the uniformity of the pancreatic mechanism in vertebra / by W.M. Bayliss and E.H. Starling.

  • William Bayliss
Date:
[1903?]
Catalogue details

Licence: Public Domain Mark

Credit: On the uniformity of the pancreatic mechanism in vertebra / by W.M. Bayliss and E.H. Starling. Source: Wellcome Collection.

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    the depressor effect was even more marked than in the case of the dog, and was often associated with vagus inhibition of the heart. On the other hand in the monkey and rabbit, the two herbivorous animals we experimented on, the depression of blood-pressure was very much less marked than in the dog and cat. In fact, on several occasions in the monkey a distinct rise of pressure was observed to accompany the secretory effect of the injection. Fig. 5. Pancreatic secretion in monkey. Injection of secretin from human intestine. Blood-pressure zero 23 mm. below time-marker. Although it is at present difficult to express quantitatively differences between the pancreatic activities of various animals, we have acquired the impression that in the carnivora the pancreas is much more active and the intestinal extract richer in secretin than in_ herbivorous animals, such as the rabbit or sheep. In the rabbit we found in every case a slight spontaneous secretion, as has been already described by other authors. On injecting secretin the rate of flow was quickened three or four times. Fig. 6. Pancreatic secretion in rabbit. Effect of injecting 10c.c. secretin solution from dog’s gut. Blood-pressure zero 38 mm. below signal.
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