Clinical studies with large non-emetic doses of ipecacuanha : [with a contribution to the therapeusis of cholera] / by Alfred A. Woodhull.

  • Alfred Alexander Woodhull
Date:
1875
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Licence: Public Domain Mark

Credit: Clinical studies with large non-emetic doses of ipecacuanha : [with a contribution to the therapeusis of cholera] / by Alfred A. Woodhull. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    man war, the moat obstinate and fatal disease the physicians had to deal with was dysentery of a very chronic character/ After other methods the ipecacuanha treatment was then tried, and with fair success; doses of live to fifteen grains of the powder were given three or four times a day; it rarely caused vomiting, except at the first dose,, sometimes not even then. Dr. Duck- worth {St. Earth. Rf.p., 1871, vii., p. 116,) quotes Akenside aa saying of the use of the drug, Ne.que interest utrum acuta nit dys- entt'.ria, an chronica: utrum sanguuiem hahnant dejectionex, an muco tantam constent.—{De Dynenteria Comnientanus* 1764, p. 39.) Duckworth (p. 143) reports a case of chronic dysentery cured by enemata of ipecacuanha, and further siiys (p. 117), It is a fashion in India to employ au injection of the drug in dysentery.f * * The plan was tried in the hospital [St. Bartholomew's] in the case of a woman, * * who was sinking apparently from uncontrollable dysenteric diarrbcea, which ensued after au opera- tion for strangulated femoral hernia. It was successful after the usual remedies had failed. No nausea or vomiting occurred. (This case will be referred to in a subsequent section of this paper.) He also quotes a successful case in a child reported by Dr. Hillier (M(id. Times and Gaz..* Jan., 1864,) but adds that when attempted in those very obstinate cases of diarrhosa which occur when the lower bowel is the .seat of tuberculosis and ulcer- ation it failed. But on the contrary we have the experience of M. Chouppe iFractilioner, No. Ixiii., July, 1874, p. 58, fr. Bui. Gen. Tlier.* June 15, 1874,) who has used it by injection with very satisfactory results in the diarrhoea of tuberculous patients and in the choleriform diarrbcea of young children. J In these cases vomiting was never observed.|| Of the seventeen cases of phthisical diarrhoaa thirteen were cured and two improved.§ t See Dr. Wliiitingliaiu's article alieudy cited. X MM. Bourdon and Chouppe followed Troussean in nsing the drug in infantile cholera, cLangiug the udmiaistiatioa from the mouth to the rf^ctum. .(PoJiehronie, op. cit, p. 19.) M. Polichronie gives iu dttiil M. Chouppe's live cases ol iulaniile cnoleia and adds one by M. Huchard. There v*ras one death in the six, which is attributed lo errors of diet. II Inflammation of the rectum, passing off when the treatment is sus- pended, Irequeully lollovi's these enemata. M. d'Ornellas, using emetine, met with it in every case; M. Chouppe, using ipecac, found it in only five cases in thii ty-lbur. (LeProrjres Medical, No. 28, 11th July, 1874.) §Polichronie {op. cit., pp. 29-31) gives details of one case of acute and three of chronic dysentery treated by enemata of ipecacuanha. One of the last was unsuccesslul.
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