Report of investigations into the pathogeny of diphtheria / conducted by Edward Curtis and Thomas E. Satterthwaite.

  • Edward Curtis
Date:
[1877]
Catalogue details

Licence: Public Domain Mark

Credit: Report of investigations into the pathogeny of diphtheria / conducted by Edward Curtis and Thomas E. Satterthwaite. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    Experiments 176 to 186 inclusive : March 22, 1875. Fresh human urine was boiled, filtered, and then charged with Squibb’s unbleached salicylic acid, as per table below. The test tubes were observed for eight days. Urine and Salicylic Acid. March 22: Tubes Prepared. 1st day after. 3 cl 3cl 4th 5 til 6tli rtn 8th Urine + Salicylic acid, i/toooo “ 1/5000 “ “ 1/4000 “ “ 1/3000 “ “ 1/2500 “ “ 1/2000 “ “ 1/1500 “ “ 1/1000 1/500 1 1 . 1 Experiments 187 to 196 inclusive : April 29, 1875. The following aqueous solutions of Squibb’s pure salicylic acid were made by the addition of a little sodic phosphate: 1: 100, 250, 500, 750, 1,000, 1,500, 2,500, 3,000, 5,000, 10,000. Two fluid drachms of each solution were put into a test-tube, and then the test-tubes were severally inoculated with one drop each of a strong, putrid beef-decoction. The tubes were finally loosely stopped with cotton. The tubes were examined at intervals, with the following result: All the solutions weaker than 1-1500 began to turn cloudy almost immediately. The fol- lowing solutions were found cloudy on the days stated respectively: 1-1500 on the 6th day, 1-1000 on the 28th; 1-750 and 1-500 were clear on the 28th day, but were found cloudy on the 74th, no observation having been made between these dates; 1-250 and 1-100 remained clear during the whole 78 days of the observation. Experiments 197 to 206 inclusive: April 29, 1875. Precisely similar experiments were made with Squibb’s unbleached salicylic acid. The results were practically identical with the foregoing.
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