On the administration of belladonna, and on certain causes which modify its action / by Henry Wm. Fuller.

  • Fuller, Henry William, 1820-1873.
Date:
1859
Catalogue details

Licence: Public Domain Mark

Credit: On the administration of belladonna, and on certain causes which modify its action / by Henry Wm. Fuller. Source: Wellcome Collection.

Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.

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    Feb. 23(] — 4gr8.of the extract. „ 24th— 6 „ 25th— 9 „ „ 26th—12 „ 27th—12 „ 28th—16 „ Mar. 1st—20 „ „ 2(1 —24 „ 3d —24 „ 4th—28 „ „ 5 th—32 „ „ 6th—32 „ „ 7th—36 „ Mar, 8th—10 grs. of the extract, „ 9th—44 „ lOth-48 „ 11th—52 „ 12th—56 „. „ 13th—60 „ „ 14th-64 „ 15th-64 „ 16th—64 „ 17th-64 „ 18th—68 „ 19th—70 „ 20th—70 Thus, up to this date, or, in other words, within twenty- six days, she liad taken 1019 grains, or rather more than two ounces of the extract of belladonna; meanwhile her appetite had remained good, and the tongue moist and clean, but red. After the first four days she was always up and playing about the ward during the day, and at night she slept soundly, but not heavily. The pupils were always large, and somewhat dilated. She never experienced any vertigo, and on one or two occasions only, the slightest indistinctness of vision. The urine, from the first, was loaded with lithates, and was of very high specific gravity, usually about 1030; and, during the last six days of her taking the belladonna it was exceedingly scanty ; so much so, indeed, that not more than seven ounces were passed each day, exclusive of what w^as passed at stool ouce daily. Its sp. gr., from the 12th to the 20th of March, ranged from 1033 to 1036. She was a long time in passing it, and seemed to experience some difficulty—not pain—in doing so. In this case the spasms were almost as severe on the 20th of March as on the day of her admission, and, therefore, although no ill effects were produced by the belladonna, its use was discontinued. After she had remained five days without medicine, the administration of sulphate of zinc in one-grain doses was commenced. The choreic symptoms at once began to subside, and as the dose of zinc was increased, which it was by the 8th of April, up to