On the administration of belladonna, and on certain causes which modify its action / by Henry Wm. Fuller.

  • Fuller, Henry William, 1820-1873.
Date:
1859
Catalogue details

Licence: Public Domain Mark

Credit: On the administration of belladonna, and on certain causes which modify its action / by Henry Wm. Fuller. Source: Wellcome Collection.

Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.

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    bowel symptoms occurred, mere omission of the mediciue sufficed to cause their cessation. Did the existence of spasm counteract the influence of the drug, and prevent their occurrence? 6thly. The urine was generally clear and acid, but scanty, and of high specific gravity, varying from 1024 to 1036. In Cases 3, 6, and 8, it frequently contained a copious deposit of crystallized lithic acid. In Cases 5, 7, and 9, it was usually loaded with lithates. In Case 3, for the space of a few hours, -whilst the patient was under the toxical influence of the drug, it became ammoniacal almost as soon as voided. 7th]y. In Case 11 some difficulty was experienced in voiding the urine throughout the period of the administra- tion of belladonna, but this was not observed in any other cases. This difficulty passed off when the belladonna was omitted. 8thly. The tongue was always moist, but unusually red, whilst the larger doses of belladonna were being taken, and the redness passed off when the drug was omitted. 9thly. Dilatation of the pupil was very uncertain. In almost every instance the pupils were large before the administration of the medicine was commenced, and they invariably became dilated soon after a dose of the medicine • was taken. The dilatation, however, was not to the degree observed when a solution of belladonna is dropped into the eye, and in most of the cases it passed off before another dose of the medicine was due. Its ordinary duration was about two hours and a half. In Case 2 excessive dilata- tion occurred for some hours coincidently with the occur- rence of sickness and purging. In Cases 3 and 11 consi- derable dilatation was pretty constant. In Case 12 the dilatation was seldom great. lOthly. In tAVO instances only (Cases 5 and 11), did the slightest indistinctness of vision occur. In Case 11 it was observed only on three occasions, and tlien to a slight degree, and was not accompanied by dryness of the throat, headache, or any impairment of the mental faculties. In