A report of microscopical & physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham.
- Timothy Richards Lewis
- Date:
- 1872
Licence: Public Domain Mark
Credit: A report of microscopical & physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham. Source: Wellcome Collection.
Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.
40/116 page 36
![[ 30 ] Post-mortem rigidity was well marked. There was a Post-mortem. Mucou s little reddish serum in the peritoneal ^veiled11,wfth8™*11 so^ft1 e pink cavity, but the intestines and mesen- liiim,nexeept above^fieo-ccc^cai tery were not congested. On laying valve> open the small intestine, the interior was found to present the usual appearances, the portion immediately above the ileo-coecal valve being unaffected, and the rest of it covered with a soft pink coating of detached epithelium. Preparations of this pink material as well as of matter scraped from the subjacent denuded mucous coat were exa- mined. The former were found to consist of cylindrical epi- . , . „ „ thelial cells, and to contain numerous The pink material crowded . .. ... .. . with epithelial ceils, and os- long serpentine VLbnones similar to cillatoria-like vibriones. ., ° „ ■*- , .... . those found m the intestines and glands of the dogs of the previous experiments. The latter preparations consisted of imperfectly developed epithelial cells, with an even greater abundance of the elongated vi- briones (Pig. 1.) which ultimately resolved themselves into a network of leptotlirix-filaments (Pig. 2). The mesenteric glands contained pinkish fluid, a pre- Fiuid in mesenteric glands paration of which was mounted in a contained long vibriones. wax-cell. When examined an hour afterwards, the gland-cells were found to be considerably dis- integrated, whilst the fluid contained great numbers of the elongated serpentine vibriones, described in the previous pre- parations, in a state of full activity. The majority of them appeared to be uniseptate with a kind of hinge joint in the middle. The rest of the abdominal organs were healthy. There was a little reddish serum in the pericardium; the right side of the heart was full of fluid blood, and the left contained a little also. A preparation of blood was as usual mounted in a wax- cell, which was examined an hour and a half afterwards, and found to contain numerous minute molecules in active mo- tion, but no distinct bacteria. Twenty-four hours after- Blood contained active mole- Wards it WUS Crowded with large cuies, but no bacteria. needle-shaped blood-crystals, and the serum had almost dried up. (cl,)—The choleraic material used being four days old. Experiment XI.—A small healthy pariah dog was put tvt * • , , * under the influence of chloroform, Material used as in Expert- Lluuvi -1-L‘ ’ ments vii-x, but oo hours ant[ four drachms of the fluid employ- ed iu Experiments VII, A III, IX and](https://iiif.wellcomecollection.org/image/b22355510_0042.jp2/full/800%2C/0/default.jpg)
