A report of microscopical & physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham.
- Timothy Richards Lewis
- Date:
- 1872
Licence: Public Domain Mark
Credit: A report of microscopical & physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham. Source: Wellcome Collection.
Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.
98/116 page 94
![[ 91 ] macerated the mucous membrane, that the epithelium had become detached, and floated in flakes in the fluid which had been introduced, and in one of the cases the sub-jacent mucous membrane had lost all appearance of congestion, whereas it was found to have retained it in the other. In the non-isolated portions of the mucous surface, the small intestine in both instances was intensely injected, otherwise the structure of the membrane was intact. It may be remarked that in this series of experiments also, a portion of the intestine for a short distance above the ileo-coecal valve was not materially affected. In connection with this series it is also to be noted that . Pericarditis, more or less distinct. Association of pericarditis , ,. „ •with peritonitis, but not with was observed in fully one-lialf of the pleuritis. ,, , • t -i cases ; that portion of the pericardial sac in immediate connection with the diaphragm was the part usually affected, together with the portion immediately attached to the sternum. Perhaps the origin of this may be explained by one of the series of Observations on the Anatomy of Serous Membranes, lately published by Drs. Burdon Sanderson and Klein, which shows that when various colouring matters are introduced into the abdominal cavity, the lymphatic vascular system of the diaphragm becomes completely injected, as also, the sternal vessels and sternal glands. The production of Pericarditis but without the co-inci- Intimate connection of the dent OCCUlTeUCe of pleurisy, by the Sthlo?y 0iwnheumauscm.c injection of various putrefying sub- stances into the peritoneum, is especi- ally worthy of note, seeing that the opinion is strongly held by many, that, as Lactic acid, when injected in a similar way (as was demonstrated by Dr. B. W. Bicliardson), pro- duces inflammation of the serous membrane of the heart, this acid must in some way be connected with the phenomena observed in Eheumatism if not in reality its cause. It seems to us that putrefying substances may, on the same grounds, lay claim to a somewhat similar relationship. With respect to the nature of the fluid produced by the Microscopical —, inflammation which had been brought r appearance . of the peritonitic fluid. on ]}y p[ie yarioUS Organic SOllltlOUS described, it may be observed that under the microscope.no difference whatever could be detected between the fluids, beyond that in some cases red blood-corpuscles formed a more prominent feature than in others, but this increased](https://iiif.wellcomecollection.org/image/b22355510_0100.jp2/full/800%2C/0/default.jpg)
