Statistical studies in immunity : a discussion of the means of estimating the severity of cases of acute disease / by John Brownlee.

  • John Brownlee
Date:
1907
Catalogue details

Licence: In copyright

Credit: Statistical studies in immunity : a discussion of the means of estimating the severity of cases of acute disease / by John Brownlee. Source: Wellcome Collection.

Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.

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    In the first place it is to be noted that, though infectious diseases in general increase in severity from youth to age, yet the date on which the disease ends is not altered but remains constant; in other words, if recovery is to take place it will take place in a person of sixty on the average at the same time as in a person of fifteen, although the percentage mortality varies enormously between these two extremes; that is to say, the forces which control the acquirement of immunity vary independently of the amount in which they are present. As an illustration of this a table (Table I.), already given in a previous paper*, is given here. It is to be noted that not only does recovery take place at the same date in the illness, but that the date of death is also sensibly constant. Likewise in the same disease it may be shown that the weakening of the body brought about by the fever varies independently of the age and of the capacity of acquiring immunity. The day on which cardiac weakening first becomes apparent TABLE I. Gases of Typhus Fever. Dr Russell’s Cases-f Age Period, Crisis, and Death. Day of Crisis or 0—U 15- -19 20- -30 so- -40 40- -50 50 — Death Recoveries Deaths R D R D R D R D R D 7 _ _ 1 _ 1 8 — — — — — — 1 — — — 2 .9 3 — 2 — 2 — — 2 — 1 1 3 10 3 1 7 1 7 — 7 2 4 5 1 3 11 3 — 16 2 11 6 3 2 11 1 1 1 12 7 1 12 — 23 1 15 2 4 5 4 2 13 7 23 2 19 13 1 6 2 3 2 U 2 — 11 1 21 — 17 5 7 2 8 4 15 5 — 7 2 7 4 2 3 3 4 — 1 16 — — — 2 2 4 — 2 1 2 1 — 17 1 1 — 2 — 1 — 1 — — IS — — — 1 — 2 — 3 — 1 — 2 10 — 1 20 — — — — — 1 — — 1 — — — 21 — — — 1 — 1 — 1 — 2 — — 22 — — — 2 — 5 — — 1 — 1 Totals ... 30 2 79 1.5 92 26 57 25 37 29 19 22 Mean Day Recoveries 12-2 12-4 12-G 12-6 12-5 12-9 „ Deaths ... Mean Da}' of Death 1 of those dying !• under 20 days J — 11 — 15-6 — 16-2 — 13-7 — 13-8 — 12-2 11 14T u-s 13-5 130 11-8 * “ Statistical Studies in Immunity. The Incubation Period and the Crisis.” P.oijal Fhilosophical Society of GUtaymv, 1906, pp. 17, 18. t Glasgow Med. Journal, 1871.
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