Carbohydrate metabolism and insulin / by John James Rickard Macleod.

  • John James Rickard Macleod
Date:
1926
Catalogue details

Licence: In copyright

Credit: Carbohydrate metabolism and insulin / by John James Rickard Macleod. Source: Wellcome Collection.

    11/386 page 7
    TABLE OF CONTENTS. CHAPTER PAGE I. The Structure of the Islets of Langerhans . . i Introductory ....... i Cytological characteristics .... 4 Enumeration of the Islets .... 8 Relationship of Islets to Pancreatic Ducts . . 13 Bibliography ....... 16 II. Structural changes in the Pancreas under various Experimental Conditions .... 18 Ligation of the Ducts . . . . .19 Pancreatic Grafts ...... 22 Pancreatic Remnants ..... 23 Bibliography ....... 26 III. The Islets in Fishes and their Yield of Insulin . . 27 Comparative Anatomy ..... 27 The Yield of Insulin from Fish Islets . . 31 Cytological characteristics of Fish Islets . . 33 The Effects following removal of the Islets (Isletectomy) ...... 35 Review of preceding evidence that Insulin is derived from the Islets .... 37 Bibliography ....... 40 IV. Pancreatectomy ....... 42 Partial Pancreatectomy . . . . 51 Bibliography . . . . . . -53 V. The History of the Preparation of Insulin . . 55 The earlier attempts to prepare Pancreatic Extracts having Antidiabetic Effects . . 55 The Isolation of Insulin ..... 62 Bibliography ...... 68 VI. The Preparation and the Chemical Properties of Insulin ....... 70 Bibliography ...... 77 VII. The Clinical History of Depancreatised Dogs treated with Insulin ...... 78 Bibliography ....... 89
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