Anatomy, physiology, pathology, dictionary / edited by W.A. Evans, Adolph Gehrmann, William Healy.
- Date:
- 1906
Licence: In copyright
Credit: Anatomy, physiology, pathology, dictionary / edited by W.A. Evans, Adolph Gehrmann, William Healy. Source: Wellcome Collection.
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![latest work of the veteran observer Hayem, who speaks with especial emphasis on the study of blood plates in anemias. He says: It is certainly wrong to neglect these elements. When their number becomes small it is always a more or less serious sign; when they become rare the retractability of the clot diminishes. . . . This double lesion rarity of the hematoblasts [blood plates] and loss of retractability of the clot is a sign of pro- gressive pernicious anemia, and is the most characteristic sign which we have of this protopathic form. If this double sign does not exist, the proper treatment will effect a cure, and one of the first signs of improvement is a rise in the number of blood plates. If the case continues to improve, further interesting changes are noted in the relation of the plates to the red corpuscles; small red corpuscles appear in increasing numbers and there is every indication that young red corpuscles are developed from the plates. Ha}^em’s observations, so far as the numerical relations of the blood plates are concerned, have been confirmed by a number of observers, including van Emden and Pratt, whose methods of numeration are free from the objections which apply to the older method of Hayem. Purpura Hemorrhagica.—In Purpura hemorrhagica the number of blood plates is enormously diminished. Van Emden and Pratt each state that the lowest counts they have ever found have been in this disease. Hayem called attention to the slowness in clotting of the blood. Helber confirms this observation of Hayem. To distinguish the blood in Purpura hemorrhagica from that of pernicious anemia, Hayem says that, in the absence of appreciable changes in form in the red corpuscles, the scarcity of hematoblasts [blood plates] and the absence of serum after the coagulation of the blood, are two signs which are constant and pathognomonic” of the disease. The few plates which are found are often of large size. The blood contains masses of small plates, but these are broken down. Fibrin threads in the clot are few, but coarse. Eecovery is ushered in by a “crise hematoblastique.” Physiology of Prostate. Jappelle and Scafa1 removed (1) Arch. Ital. de Biol., May, 1906,](https://iiif.wellcomecollection.org/image/b28061081_0045.jp2/full/800%2C/0/default.jpg)
