On the growth of the albino rat (Mus norvegicus var. albus) after castration / by J.M. Stotsenburg.

  • Stotsenburg, J. M.
Date:
1909
Catalogue details

Licence: In copyright

Credit: On the growth of the albino rat (Mus norvegicus var. albus) after castration / by J.M. Stotsenburg. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    ON THE GROWTH OF THE ALBINO RAT (MUS NORVEGICUS VAR. ALBUS) AFTER CASTRATION. By J. M. Stotsenburg, M.D., Curator and Junior Associate in Anatomy at The Wistar Institute. No systematic study of the growth of any mammal after cas- tration has yet been reported. The existing literature on castra- tion deals mainly with its application to domestic animals for economic purposes. There are, however, some general descrip- tions and measurements made during life on human castrates; Matignon (’96), Pelikan (’76) and Jameson (’77), also several reports of dissections of eunuchs; Ecker (’64-’65), Gruber (’47), Lortet (’96), Becker (’99), Tandler and Grosz (’09), together with a considerable number of investigations on animals showing the dependence of the secondary sexual characters on the integrity of the testes; Bibbert (’98), Borig (’99, ’99A, ’01), Sellheim (’98) and Foges (’02). Further we have some literature, based on animal experiments, touching the interdependence of the hypophysis and of the thy- roid gland on the testes: Fichera (’05, ’05A), Bichon and Jean- delize (’05, ’05A). In chickens, rabbits and dogs studies have been made on the growth of parts of the skeleton, especially the growth of the limb bones which become longer than normal: Poucet (’78), Bichon and Jeandelize (’05B, ’05C), Sellheim (’99). Finally, McCrudden (’08) has studied the metabolism of cas- trated dogs, using the excretion of salts as an index. These experi- ments show the operation to be without any marked influence on metabolism in this animal. The chief result of the experimental work is, therefore, to show that many secondary characters in mammals and birds are modi- . fied in their development by injury or removal of the testes, and that the latter probably produce their effect through some form of internal secretion, as shown by the observations of Walker (’08). The growth of parts of the skeleton and some of the ductless glands are also in a measure and in some animals affected by castration. In the present communication, however, we shall consider the influence of castration only in relation to the increase in body Proceedings of the Associat:
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