The natural history of cow-pox and vaccinal syphilis / by Charles Creighton.

Date:
1887
Catalogue details

Licence: Public Domain Mark

Credit: The natural history of cow-pox and vaccinal syphilis / by Charles Creighton. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

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    Jenner’s new opportunist doctrine of pi’imary and secon- dary, or essential and unessential effects of cow-pox inocu- lation. Susan Phipps, aged seven years, was inoculated on December 2nd with matter which had been taken from the cow on November 26tli, and dried on a quill: the vesicle did badly, became a phagedenic ulcer, the size of a shilling, and healed by granulations after several weeks. From her matter was taken on the eleventh day by “ Mr. D., a neighbouring surgeon,” and probably also by Jenner himself; at all events, Mary Hearn, aged twelve years, was inoculated with matter taken from the arm of Susan Phipps, and in her case also “ the progress]of ulceration ” had to be checked about the end of the second week and beginning of the third, by repeated applications of mercurial ointment. There is nothing known of any stock having been raised with the matter from Susan Phipps, taken by “ Mr. D., a neighboiiring surgeon,” nor does Jemier say that he con- tinued the succession beyond Mary Hearn (the second remove from the cow). In fact, he was again stopped, either by the fear of ulceration, which, as we shall see, had been secretly haunting him all through his experiments, or by some other obscure cause. It was not until he received, on the loth of February, 1799, a thread soaked in lymph from Woodville’s continuous series of vaccinations in London, that Jenner was able to establish a supply at Berkeley. He inoculated his nephew, Stephen Jenner, aged three and a half years, with one half of the thread, and James Hill, aged four years, with the other half, both of whom wei'e infected satisfactorily;* and from James * Further Observations, cd. cit., pp. 130—1.32. B