On the formation of uric acid in animals : its relation to gout and gravel, together with an explanation of the therapeutic effects of some of the remedies used in the treatment of those disorders / by P.W. Latham.

  • Peter Wallwork Latham
Date:
1884
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Licence: Public Domain Mark

Credit: On the formation of uric acid in animals : its relation to gout and gravel, together with an explanation of the therapeutic effects of some of the remedies used in the treatment of those disorders / by P.W. Latham. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    refer to two of the most trustworthy of modern times. Sir James Paget1 says, “ disturbance in the nervous system in some form and part may be re- garded as a factor in every case of gout. There are reasons enough for thinking that changes in the nervous centre determine the locality of each gouty process, while changes in the blood and tissues deter- mine its method and effects; a,nd that thus we may explain the symmetries of disease in gout—some- times bilateral, sometimes antero-posterior—and thus its metastases. But these changes are a part of its pathology which is not yet clinical.” Dr Edward Liveing2 writes, “There can be no question then, I think, as to the frequent con- nexion of megrim, whether in its blind, sick, or simply hemicranial forms, with a gouty diathesis, and its occasional replacement by fits of regular gout. Megrim, however, is far from being the only neurosis which is thus associated with gout; a similar connexion may be traced in the case of asthma, angina pectoris, gastralgic paroxysms, and certain forms of transient mental derangement. The con- 4 sideration suggests an interesting inquiry as to the 1 Clinical Lectures and Essays, 1879, p. 382. 2 On Megrim and Sick-headache, 1873, pp. 404—5. 3—2
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