On the degeneration of the neurone / [Sir F.W. Mott].

  • Frederick Walker Mott
Date:
1900
Catalogue details

Licence: In copyright

Credit: On the degeneration of the neurone / [Sir F.W. Mott]. Source: Wellcome Collection.

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    examined there was not only degeneration, discoverable by the Marchi method, of the whole cortico-spinal neurones, but of the lateral branches which pass off from the axis-cylinder processes to enter the corpus callosum (vide fig. 49). This Fig. 48. — Section of lower portion of grey matter of the motor area of the cortex, showing absence of large pyramidal cells and replacement by Deiter’s cells. This occurred in little isolated foci. Fig. 49.— Section of the corpus callosum from lateral sclerosis showing large black degenerated fibres a case of amyotrophic in transverse section. degeneration of the motor fibres in the corpus callosum strongly favours the primary degeneration theory of the origin of the disease being a nutritional degradation of the neurones them- selves, independent of external vascular or' supporting tissue