Selected researches in pathology / by Alex. Gunn Auld.

  • Auld, Alexander Gunn.
Date:
1901
Catalogue details

Licence: In copyright

Credit: Selected researches in pathology / by Alex. Gunn Auld. Source: Wellcome Collection.

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    admixture with blood oozing from the hepatic veins. The spleen was much enlarged, fairly firm, and intensely con- gested. It would seem, in point of fact, that this haemo- globinaemia is characterised by a great determination of blood to the viscera. Under the microscope the liver showed nothing of much moment; the nuclei of the cells seemed, however, to be much stimulated. The blood in the capillaries was hardly to be distinguished from normal blood. The spleen was intensely full of blood, many of the corpuscles seemed to be disintegrating within the cells of the pulp, and a certain quantity of pigment was present. The capillaries of the lung were highly swollen with blood. The kidneys showed extreme vascularity of the glomeruli, with occasional lnemorrhages into the capsular space. The lumina of several of the cortical tubes were filled with blood. The urine was, as stated, saturated with hiemoglobin, and it deposited epithelium, some red blood corpuscles, and red granular matter which I took to be fragments of blood corpuscles. Subacute Poisoning with Phenylhydrazin. In the next place, a subacute poisoning was induced by administering small doses of the drug from day to day for a period of about eight days. On one or two days no injection was given. In these cases the post-mortem appearances were as follows : The duodenum contained much green-stained stuff; the gall bladder was well filled with a dark olive-green, but perfectly fluid bile; and the hepatic, cystic and common ducts were likewise well filled with a similar bile; the duodenum was bulged into a distinct pouch just opposite the entrance of the common duct, and in one case, in which the animal had been kept exclusively on a diet of bread and milk, this pouch con- tained a bile-stained mucus of extraordinary viscidity, adhering with such tenacity to the wall that it could with