A practical treatise on materia medica and therapeutics / by Roberts Bartholow.
- Date:
- 1888
Licence: Public Domain Mark
Credit: A practical treatise on materia medica and therapeutics / by Roberts Bartholow. Source: Wellcome Collection.
Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.
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![His observations were made with chloroformic solutions of aconi- tine, atropine, strychnine, and morphine. Waller further ascertamed that alcohol mixed with chloroform did not retard absorption, but al- cohol alone caused an outward osmotic flow. It follows from these facts that, if, in the application of a medicinal agent to the skm by the endermatic method, the object be to promote absorption the remedy should be dissolved in chloroform, or in a mixture of alcohol and chlo- roform, and not in alcohol alone, or in water. _ EpiDERMATic.-This method differs from the enepidermatic m that friction is employed to promote absorption by forcing the medicament between the cells of the epidermatic layer. Many agents are used m th1; way,as mercurial ointment in syphilis, cod-liver oil, and o her fa s In wasting diseases, and ointments of various kinds for the relief of local lesions, etc. The evidence is conclusive that by this mode -riS^^^^^^t^ermis is the chief obsta^e to _ absorptioD, it is sometimes removed by bhstenng, so that the med.ca ment may come into immediate co.taet with the derma. The mode Tp 0° eding by the epdermatic method is as follows : a p.ece of flan- nel patent ifnt, or cotton cloth, is moistened with aqua ammoma^, and wtn plaoea on the skin is covered with oiled silk to P--t evapora- TLon When the blister is raised, the epidermis is removed with sc,»- Ts! A less paintnl, but slower method, is the app .cation o a ean- tharides-plaste'r. followed by a poultice to r.s^^^^^^^^ but the opinion of Brown-Se,uard is hardty ^^^^^^^ „e use of ^ ^rilltrobTec^^^^^^^^ the endermatic unwisely neglected, mere aie ueciu j • ulceration method: it is painful.; ^^^^rvU^^ 'l^'^^X^^^ of an intractable character may ^^'^^'^'^^^^ . .^ay be con- favor • it may be used in cases of irritable stomaeii ^^^]y •led with counter-irritation ; it is sometimes quite effective. II. THROUGH THE INTERNAL INTEGUMENT. rubtTrCi-r= tract. Insufflation-tubcs wiin contained in a chamber](https://iiif.wellcomecollection.org/image/b21963733_0036.jp2/full/800%2C/0/default.jpg)
