Cells of immunoglobulin synthesis / edited by Benvenuto Pernis, Henry J. Vogel.

Date:
1979
Catalogue details

Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: Cells of immunoglobulin synthesis / edited by Benvenuto Pernis, Henry J. Vogel. Source: Wellcome Collection.

    455/464 (page 427)
    Index A Adult animals, tolerance phenomena, 9 Alloantigens antibodies, 309, 313-321 biochemical analysis, 317-320 linkage analysis, 314-317 Amino acid sequence human immunoglobulin mutant, 90-94 of fj, chains, 184 of myeloma proteins, 99-112 Anti-p -azophenylarsonate antibody (anti-Ar antibody), idiotypes, 335-342 Antibody, see also Monoclonal antibody role of Fc portion in immune regulation, 223-252 synthesis, 113 Antibody diversity, generation, 33-44, 59, 287-289, 295-300 Antibody response enhancement with passive antibody, 225 inhibition with passive antibody, 223- 225 Anti-dextran antibodies, diversity, 297- 300 Anti-dextran hydrids, 305 Antigen B-cell triggering, 259-266 categories, 257, 258, 260-262 multivalent, 260 suppressive mechanism, 266-268 Antigen-antibody complexes binding on lymphocytes, 227-231 proliferative response, 234, 235 regulation, 223-227 Antigen binding variants, 101-107 Antigenic stimulation, modes of В cell, 259-266, 269, 270 Anti-idiotypic antibodies, immune system regulation, 343-355 Anti-immunoglobulin antibodies effect on В lymphocyte maturation in¬ duced by LPS, 190-196 on growth and maturation of В cells, 209-221 Anti-(T,G)-A~L idiotypes, genetic control and cellular expression, 371-380 Autoradiogram s, of antigens, 316, 317 Autoradiography, 4 p-Azophenylarsonate group (Ar), anti-Ar antibodies, 335-342 С Cambier dilemma, 8 Capping, of surface Ig-ligand complexes, 200-202 Carboxypeptidase treatment, of l[3,5- ^H]tyrosine radiolabeled membrane fji chains, 175, 183 Cell, see also Pre-B cell differentiation, hybridomas in, 291 somatic rearrangement and gene con¬ trol, 30 T-independent and T-dependent, 6, 8 Cell hybrids, see Hybrids Clonal abortion theory, of В lymphocyte tolerance, 3, 5, 7, 10 Clonal diversity, of pre-B cells, 419, 420 Clonal dominance, 337-342 ontogeny, 357-369 Clones, properties of mutant, 115 Clonotype, В cell, 253-255, 260 427