Studies in the treatment of malaria. IV, Intramuscular injections of amylopsin and trypsin in simple tertian malaria / by J.W.W. Stephens [and others].
- Date:
- 1917
Licence: Public Domain Mark
Credit: Studies in the treatment of malaria. IV, Intramuscular injections of amylopsin and trypsin in simple tertian malaria / by J.W.W. Stephens [and others]. Source: Wellcome Collection.
3/12
![[Reprinted from the ‘ Annals of Tropical Medicine and Parasttology,’ Vol. XI, No. 2, August, 1917] 165 STUDIES IN THE TREATMENT OF MALARIA IV. INTRAMUSCULAR. INJECTIONS OF AMYLOPSIN AND TRYPSIN IN SIMPLE TERTIAN MALARIA BY Binv-Gous Jon, Wa: Wo STEPHENS, *RJA.M.C. W. YORKE B= BUACKLOCK J. W. S. MACFIE AND C. FORSTER COOPER From the Liverpool School of Tropical Medtcine (Received for publication 10 May, 1917) Lambelle (1913) stated that he had treated successfully twelve cases of malaria, British soldiers in Upper Burma, by intramuscular injections of the ferments amylopsin and trypsin. Fretz (1914) records the results of treatment of nineteen cases by this method. He writes: ‘Far from being, as I had hoped, of the nature of a sterilisans magna, 1 found that it was in some cases rather a useless and painful operation. It, however, seems undoubtedly to have some effect on the parasites in fresh infections, and better results were obtained in those cases with a longer interval between the injections.’ In view of these conflicting statements we determined to put the treatment to the test. The preparations used by us were Injectio Trypsini and Injectio Amylopsini, Fairchild Bros. and Foster, as recommended by Lambelle. The contents of one ampoule of trypsin and one of amylopsin were taken up in a IO C.c. syringe, which was then filled with normal saline. The injection was made into the muscle below the spine of the scapula. In every instance the injection was given between 10 and 11 a.m. Where more than one injection was given the interval between the injections was two days.](https://iiif.wellcomecollection.org/image/b3344853x_0003.jp2/full/800%2C/0/default.jpg)
