Gout : its pathology and treatment / by Arthur P. Luff.

  • Arthur P. Luff
Date:
1898
Catalogue details

Licence: Public Domain Mark

Credit: Gout : its pathology and treatment / by Arthur P. Luff. Source: Wellcome Collection.

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    tendency or vice in common, namely, the tendency to uratosis—that is, to the deposition of sodium biurate. He considers it is more accurate, instead of speaking of ordinary gout and saturnine gout, to speak of gouty uratosis and saturnine uratosis. It appears to me that gout and plumbism have more in common than this tendency to uratosis —that is, to the deposition of sodium biurate—in that they both have the same tendency to cause the presence of an excess of urates in the blood. The association of lead-poisoning with gout has been repeatedly observed, but Oliver * states that in the north of England this intimate relationship between gout and lead-poisoning is not seen. He is not satisfied that the reason why gout is so little known in the north as a symptom of lead-poisoning, while it is so common in the south, is entirely due to the difference in the drinking habits of the people—whisky being the general alcoholic drink in the north and malt liquor in the south. At the same time he confesses his inability to offer any further explanation. I am of opinion that the influence of lead in producing gout depends solely on the extent to which the kidney parenchyma is damaged. With much damage done to the kidney cells, whose function it is to excrete uric acid, absorption of quadriurate into the blood occurs; the subsequent development of an attack of gout entirely depends on the amount of absorbed quadriurate, which in its turn depends on the amount of kidney mischief. * Goulstonian Lectures on Lead Poisoning, 1891. II
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