Licence: Public Domain Mark
Credit: Outlines of human pathology / by Herbert Mayo. Source: Wellcome Collection.
Provider: This material has been provided by the Francis A. Countway Library of Medicine, through the Medical Heritage Library. The original may be consulted at the Francis A. Countway Library of Medicine, Harvard Medical School.
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![these instances, instead of becoming dry and white, in four or five days generally assume a light red tint, which gradually deepens: a gelatinous exudation is then poured out, which coagulates upon the bone; and, receiving vessels from it, becomes a layer of organized and florid granulations, that unite with those produced by the neighbouring soft tex- tures, and close or fill up the wound. In the reparation of a compound fracture, the substance of the bone having its vascularity increased, appears to contribute more actively to its ov/n reparation than in a simple fracture. The whole wound equally inflames, suppurates, granulates: it is in these granulations that the provisional callus is formed. If the violence done to the bone has been more consi- derable, or if the constitution, or the bone, be already dis- eased, partial necrosis takes place. The exposed surface remains dry and white, and after a few weeks is thrown off as a thin plate or scale of bone. The bone is then said to exfoliate. The thin plate of bone, or ring (which is its shape if it follow an amputation), is called an exfoliation. The surface from which an exfoliation has separated, is co- vered with granulations, the growth and ossification of which replaces, in some degree, the substance lost. A person about thirty years of age had the tibia grazed by a blow, and denuded of periosteum. The outer shell to the depth of two lines, and the length of four inches, was necrosed. It separated in twelve weeks, [c?. 37.] In a compound fracture, it often happens that the most projecting point or edge of the broken bone is necrosed, and exfoliates. Where there has been great violence, or pre- vious disease, a considerable extent of bone is often ne- crosed, [c. 38.] Accidents of this kind again display the difference in the restorative forces which different kinds of bone possess. After amputation of the thigh or humerus, three, four, or five inches of necrosed bone occasionally come away. A person thirty-four years of age, who had lived intemperately, was admitted into the Middlesex Hospital with compound fracture of the leg: great swelling and inflammation fol- lowed ,' and on the sixth day, violent arterial hemorrhage.](https://iiif.wellcomecollection.org/image/b21066735_0070.jp2/full/800%2C/0/default.jpg)


