Licence: Public Domain Mark
Credit: Outlines of human pathology / by Herbert Mayo. Source: Wellcome Collection.
Provider: This material has been provided by the Francis A. Countway Library of Medicine, through the Medical Heritage Library. The original may be consulted at the Francis A. Countway Library of Medicine, Harvard Medical School.
90/640 page 54
![and doughy, and had forced out about a pound in weight of medullary substance. The following day I amputated the limb above the knee. The head of the tibia was found expanded into a thin membranous shell, with very little bony matter in its texture, the cavity being occupied partly with soft yellowish substance resembling the medulla of the brain, partly with coagulum. The deposit of medullary sub- stance extended some distance into the cancelli of the shaft of the bone. [d. 79.] The tibia, humerus, femur, are the bones most commonly attacked with medullary sarcoma: the other bones of the extremities occasionally. The flat bones, however, do not escape. I have seen the disease in the ilium and in the cranial bones [d. 81.], and in the sternum and ribs. [d. 81*.] I have known an instance, in which a medullary tumour in a rib was so circumscribed and moveable, as to have been supposed a tumour of the breast, which the surgeon, as he told me, would have thought of removing by an operation, but for the evidence of other and coexisting disease. 4. Fibrous Sarcoma. — There is a form of malignant dis- ease of bone, of which the texture is firm, white, and fibrous. Its origin, I believe, and its place, to be ex- clusively periosteal. This disease is met with on the tibia. If simply removed from the bone, it grows again: the limb must be amputated. [d. 83.] The same growth is liable to form upon the cranial aspect of the dura mater, to push its way through the bone by ab- sorption, and to project great masses of sarcomatous growth upon the head and face. [d. 82.] 5. Cystlike Tumour. — In the heads of the bones of the extremities, and in the lower jaw, a disease, which has the general characters of malignant growth, is found, when examined after death or amputation, to consist in a great cyst, or series of cysts, containing gelatinous liquid. It is probable that these tumours have some relation, as yet un- defined, to fungus hematodes. [d. 86. 87.] 6. Melanosis is sometimes, but rarely, met with in bone. Mr. Langstaff' has more than one specimen of this dis-](https://iiif.wellcomecollection.org/image/b21066735_0090.jp2/full/800%2C/0/default.jpg)
