Acute poliomyelitis / by George Draper.

  • George Draper
Date:
1917
Catalogue details

Licence: Public Domain Mark

Credit: Acute poliomyelitis / by George Draper. Source: Wellcome Collection.

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    of the right arm marked. Slight weakness of the anterior tibial muscles on one side. Discussion.—This case belongs to the dromedary group, but the stage of meningeal invasion is not sharply marked, nor are the signs of meningeal invasion great. The first puncture, at 48 hours after the second onset showed 39 cells and no serum was given in consequence. The next day weakness of the right deltoid appeared. Two doses of serum were then given, 20 c.c. in all. There was no doubt that the serum was delayed in this case owing to the very slight reaction found in the spinal fluid at the first puncture. A REPORT OF TWENTY-SIX CASES By Drs. Amoss and Chesney From Journ. of Exp. Med., 1917, XXV, 581 Group I. Cases Showing Paralysis at the Beginning of the Treatment Class I. Paralysis Extending ' Case 1.— Male. Age 33 years. September 2, 1916. Malaise, headache, and vomiting. Sept. 3. Unable to bear weight on legs. Sept. 4. Admitted to hospital. Legs completely paralyzed. No tendon reflexes. Cerebrospinal fluid shows 280 cells per c.mm. and increased globulin. Bladder, bowels, diaphragm, abdominal and thoracic walls, and upper extremities normal. Sept. 5. Bladder paralyzed; no abdominal movement during respiration; using accessory muscles of respiration; deltoids weak; cyanosis. On Sept. 5, ro c.c. of serum were injected intraspinally and 20 c.c. intravenously. The cyanosis gradually increased, and death resulted from respiratory paralysis 1o hours after the injection. No obvious influence on the course of the disease was exerted by the injections of serum. Case 2.—Female. Age 10 years. September 22, 1916. Headache, nausea, fever, and abdominal pain. Sept. 23. Temperature 103°F. Pain in back and in right leg; drags right foot... Sept. 25. Admitted’ to hospital. Temperature 102:6°F.; pulse 112; respirations 30. Neck and back muscles stiff; flaccid paralysis of both legs; bladder functions. Sept. 26,6P.M. Left deltoid paralyzed; dyspnoeic; employs accessory muscles of respiration; no respiratory move- ment of abdominal wall; bladder paralyzed. Cerebrospinal fluid contains 270 cells per c.mm.; globulin increased. | On Sept. 26, 20 c.c. of serum were given intraspinally and 60 c.c. subcutaneously. Sept. 27, 8 P.M. Temperature 99.8°F.; pulse 102; respirations 30. Abdominal muscles move with respiration. Sept. 28. Abdomen moves freely; left deltoid responds but not yet normally; bladder inactive. Sept. 30. Bladder acting; no change in leg condition. The history of the acute stage of this case readily divides itself into two periods. The first (a) takes in the time up to and including the paralysis
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