The sources and modes of infection / by Charles V. Chapin.

  • Charles V. Chapin
Date:
1912
Catalogue details

Licence: In copyright

Credit: The sources and modes of infection / by Charles V. Chapin. Source: Wellcome Collection.

Provider: This material has been provided by London School of Hygiene & Tropical Medicine Library & Archives Service. The original may be consulted at London School of Hygiene & Tropical Medicine Library & Archives Service.

    55/506 (page 37)
    Typhoid Bacilli in Urine. — Typhoid bacilli were noted in the urine as early as 1886 by Hueppe,1 and similar find- ings were reported in succeeding years by many other ob- servers. The first extensive study of this condition was made by Richardson in 1898.2 The bacilli are usually not found in the urine until the later stages of the disease, but are occasionally observed earlier, as by Connell,3 on the seventh day. They are usually in large numbers and often in pure culture. Richardson found them present in about 23 per cent of all cases examined, and earlier and later observers give about the same figures. Thus Connell tab- ulated 621 reported examinations, of which 24 per cent were positive. The bacilli generally continue in the urine for a while after recovery, but usually disappear within three months. Oftentimes the presence of the bacillus is not accompanied by symptoms referable to the urinary tract. Often, however, cystitis develops, which may persist an indefinite time, accompanied by the presence of the bacilli in the urine. The pelvis of the kidney may also be attacked by the bacilli, and foci of infection may be found in the kidneys themselves. As early as 1889 Konzajeff 4 reported finding in the kidneys infarctions containing typhoid bacilli. Marchildon5 has recently reported two cases in which the presence of typhoid bacilli in the urine was due to their growth in the seminal vesicles and the prostate, and Gould and Quails6 found the bacilli in the prostatic fluid of 1 of 19 convalescents. Typhoid Bacilli in the Sputum. — Pratt, Peabody and Long, previously quoted, cite several observers as finding 1 Hueppe, Fortschr. d. Med., 1886, IV, 448. 2 Richardson, J. Exper. M., N. Y., 1898, III, 349; 1899, IV, 19. 3 ConneU, Am. J. M. Sc., Phila. and N. Y., 1909, n. s., CXXXVII 637. 4 Konzajeff, Centralbl. f. Bakteriol. [etc.], Jena, 1889, VI, 672. 6 Marchildon, Am. J. M. Sc., 1910, CXL, 74.