Syphilis / by V. Cornil ; translated, with notes and additions, by J. Henry C. Simes and J. William White.
- Victor André Cornil
- Date:
- 1882
Licence: Public Domain Mark
Credit: Syphilis / by V. Cornil ; translated, with notes and additions, by J. Henry C. Simes and J. William White. Source: Wellcome Collection.
Provider: This material has been provided by The University of Leeds Library. The original may be consulted at The University of Leeds Library.
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![than with the adult, ov the interstitial orchitis may be unilateral and very irregularly disti'ibutcd. Tlie lesion consists in small collections of round embryonal cells, resembling lymph cells, arranged in the connective tissue around the artei'ioles which come from the tunica albuginea. These islands of embryonal tissue are arranged similarly to those met with in the livers of new-born syphilitic children, and may be described as small gummata. The lesion is accompanied by a more or less marked diffused interstitial orchitis. Or there is only seen a thick- ening from the new formation of small round cells of the connective tissue of the testicle. The seminal ducts are all surrounded with these cells, and the gland undergoes a very notable hypertrophy. The cells within the ducts become granulo-fatty and atrophied. The ducts are also ati'ophied. These changes vei-y closely resemble those found in a syphilitic testicle of an adult. It must not, how- ever, be forgotten, that the testicle of a new-born child, in the normal state, contains embryonal tissue and not fibrous connective tissue. Therefore, in order to study a syphilitic testicle of a new-born child, or any of the lesions of hereditary syphilis, the normal appearances of these organs, according to the age of the child, must be known. The symptoms of this affection are the hypertrophy, the weight, and the general or nodular induration of the testicles. Children suf- fering with this disease, usually die early from involvement of some important organ. [Henoch reports^ seven cases of disease of the testicles accompany- ing infantile syphilis, these being enlarged, hard, and inelastic, and frequently nodulated. The children were from three months to two and one half years of age, and the diseased condition usually improved under the use of mercury. In the case of one child, aged two and one-half years, the general appearances had vanished after thirty in- unctions of fifteen grains each of mercurial ointment. The swelling of the testicles did not disappear, and the child dying three months later of measles with diarrhoea, the autopsy showed both testicles still very large and indurated. Microscopical examination proved extensive in- terstitial hypertrophy of the connective tissue, most strongly developed in the corpus Ilighmori. No gummata were found. This case, like a case of Despr^s, goes to prove that Avhen fibroid new formation is already present as the result of inflammation, no [' Sclimidt's Jahrbuch. I3d. 178, No. 4.]](https://iiif.wellcomecollection.org/image/b2151852x_0423.jp2/full/800%2C/0/default.jpg)
