Syphilis / by V. Cornil ; translated, with notes and additions, by J. Henry C. Simes and J. William White.
- Victor André Cornil
- Date:
- 1882
Licence: Public Domain Mark
Credit: Syphilis / by V. Cornil ; translated, with notes and additions, by J. Henry C. Simes and J. William White. Source: Wellcome Collection.
Provider: This material has been provided by The University of Leeds Library. The original may be consulted at The University of Leeds Library.
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![siclious commencement of nephritis, usually far on in the disease, but occasionally arising precociously, or within a year after infection. The latter was, however, very rare. His experience was that the iodide of potassium sometimes was useful in these cases ; and that the prognosis was generally very bad.'] The renal lesions of tertiary syphilis consist in gummous forma- tions and amyloid degeneration of the vessels. Syphilitic gummata of the kidney are infrequent. In 18G4 I ob- tained a kidney which contained twenty-one of these tumors in its cortical substance. It occurred in an old woman, who during life suffered with albuminuria and anasarca.^ The liver was riddled with characteristic gummous neoplasms. The kidneys shoAved an amyloid degeneration of the vessels and a parenchymatous nephritis. The gummata did not differ from these new formations found elsewhere. Three zones were discernible: 1st, a peripheral inflammatory zone in which the connective tissue infiltrated with small cells separated the uriniferous tubules, the glomeruli, and vessels of the kidney ; 2d, a middle zone in which the connective tissue predominated, but where tbe glomeruli and some tubules were seen separated from one another and filled with the neoplasm ; 3d, in the centre the fibrous tissue con- taining small, atrophied, and granular cells ; here were still recognized atrophied and fibrous glomeruli. To the unaided eye, the centre of •[Fig. 84. The peripheral portion of a gummous growth iu the Icidnoy, showing tho amall-ceUed granulation tissue in the intertubular tissiio. X 200. (Green)] the gummata were yellow, while at the periphery they appeared gray, and in contact with the renal parenchyma they were more or less congested. In connection with Coyne I had the opportunity of examining a ['■ The Britisli Medical .Journal, Aug. 23, 1879.] ' Cornil, These de doctorat sur les 16sions anatomiques du rein dans I'albumi- nurie, page 50, 18G4.](https://iiif.wellcomecollection.org/image/b2151852x_0426.jp2/full/800%2C/0/default.jpg)
