Practical observations on the inoculation of the cow-pox: to which is prefixed a compendious history of that disease / [John Addington].
- Addington, John
- Date:
- [1801]
Licence: Public Domain Mark
Credit: Practical observations on the inoculation of the cow-pox: to which is prefixed a compendious history of that disease / [John Addington]. Source: Wellcome Collection.
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![[ >6 ] veficle ;—its centre continuing flat, and exhibiting a darker coloured fpeck, which reprefents the cuti- cle flill adhering in that fpot to the fkin underneath. ■—From this time the tumor enlarges, and nils with a limpid fluid, till about the 8th, nth, or icth day, when (if not before) the difeafe of the conflitution takes place. This dileafe in its fevered: form, is exactly the fame as has been deferibed in the Cafual Cow-Pox—Pain and forenefs in the inoculated part and in the arm pit:—fhiverings, and afterwards increafed heat ; wearinefs, pains in the limbs, naufea, vomiting, and head-ach.—But, in far the greater number of iultances, eipecially in children, the indifpofition is fo flight as to he IcarceTy, or not at all perceptible; or it conlifts of a few hours of increafed heat, peeviflinefs and refllefsnefs. At molt, it difappears in a day or two, without the ap- plication of any remedy. About the fame period, a linking alteration takes place in the arm; the occurrence of which, at this juncture, is iullly CQnfldered as an infallible token of the proper af- fection of the fyflem ;—The inflammation, which before was confined to the bale of the tumor, now fpreads around it, more or lefs rapidly, to the extent of one or two inches, fometiines more : exhibiting a pink, a fcarlet, or even a crimfon colour; and at- tended with evident levelling and hardnefs of the in- teguments. No fooncr has this inflammation taken place, than the veficle, in which the fluid continues limpid throughout; no longer inCreafing in fize, be- gins to dry up : and in two or three days more, the red colour of the furrounding fkin fades ; the (Veil- ing declines; and the fore in its lail llage, is covered with a thick dark-colourcd fervh, not unaptly com- pared to a dried tamarind (tone, which adheres for ten](https://iiif.wellcomecollection.org/image/b22042775_0024.jp2/full/800%2C/0/default.jpg)


