Volume 1

Reports of the commission appointed by the Admiralty, the War Office, and the civil government of Malta, for the Investigation of Mediterranean Fever / under the supervision of an Advisory Committee of the Royal Society.

Date:
1905-1907
Catalogue details

Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: Reports of the commission appointed by the Admiralty, the War Office, and the civil government of Malta, for the Investigation of Mediterranean Fever / under the supervision of an Advisory Committee of the Royal Society. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

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    Experiment II. A small, hecalthy, male monkey, which had been kept under obser- vation for 28 days. Weight 4 lbs. 9 ozs. No reaction 1—10. November 16, 1903. This monkey was inoculated into the extensor muscles of the left thigh with 1 c.c. of an emulsion, made from three tubes of M. melitensis (first generation) in 2 c.c. of broth. This experiment was carried out to prove that the growth, obtained from the peripheral blood of G. F., was the M. meUtends. November 24, 1903. The monkey appears perfectly well. Weight 4 lbs. 8 ozs. Immediate agglutination reaction 1—400. November 27,1903. Weight 4 lbs. 8 ozs. Immediate agglutinatioii reaction 1—400. The monkey was given a second injection of the contents of one tube, from same patient, into the muscles of the right thigh. December 8, 1903. The monkey has remained perfectly well. Weight 4 lbs, 8 ozs. Agglutination reaction 1—200. January 3, 1904. Monkey in good health. Agglutination reaction 1—200. June 10, 1904. This monkey still reacts 1—10. The following chart represents the temperature, taken in the axilla: DATE OcC. i30i Nov. If 20 il a U L4 26 Z7 IB 23 X il 1 I i 4 5 6 7 8 3 10 II IZ 15 14 15 16 17 18 io^° 103 102° lOl ioo° 99° 36° \ \ s DATE Dec. ZD 21 22 23 gf 25 26 27 28 23 50 1 Z J 4 5 6 7 6 3 10 II IZ 13 M- 15 16 17 18 15 ZD 104° 105° 102° lOl ° ioo° 99° 98° / / K *^ / / A / / i \ [liemartcs.—This is also a very unsatisfactory temperature chart. The high agglutination reaction is, however, a strong argument that Staff-Surgeon Gilmour is dealing with M. melitensis.—Ed.] Ed'periinent III. The following experiment was carried out to prove that the coccus, obtained from the knee-joint of F. B., age 21, was the M. melitensis. December 5, 1903. A male monkey, which had been under observa- tion for a week, was inoculated into the extensor muscles of the left