On the existence, within the liver cells, of canaliculi which are in direct communication with the blood capillaries / by E.A. Schäfer.

  • Edward Albert Sharpey-Schäfer
Date:
[1902]
Catalogue details

Licence: In copyright

Credit: On the existence, within the liver cells, of canaliculi which are in direct communication with the blood capillaries / by E.A. Schäfer. Source: Wellcome Collection.

Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.

    4/8
    [From the Proceedings of the Physiological Society, January 18, 1902.] On the existence, within the liver cells, of canaliculi which are in direct communication with the blood capillaries. By E. A. SCHAFER, c (From the Physiological Laboratory of the University of Edinburgh.) The specimens shown are from a liver which was injected with acid carmine gelatine from the portal vein. The blood vessels are full of the injecting material which has also passed into fine varicose canaliculi within the liver cells. There is no injection in the intercellular bile canaliculi, nor in perivascular lymphatics, nor between the cells. There is no diffusion of carmine nor any staining of the cells or nuclei by carmine. It may therefore be inferred that the injection has passed directly from the blood vessels into the liver cells; indeed here and there one can see what appear to be such direct communications. The specimens of liver which show these appearances are from the cat and rabbit, and they have been preserved (in spirit) in this Laboratory for many years; probably since about 1886. During that time they have been frequently used for distributing specimens of Liver of rabbit injected from the portal vein. The injection has passed into canalicuh within the liver-cells. injected liver to members of the class of Histology. The fact that the injection has passed into the cells must therefore have been seen by many persons—Prof. Carlier tells me that he noticed it and drew Prof. Rutherford's attention to it—but the extreme importance of