New methods of treatment / by Dr. Laumonier ; tr. and ed. from the 2nd rev. and enl. French ed., by H.W. Syers.
- Jean Laumonier
- Date:
- 1904
Licence: Public Domain Mark
Credit: New methods of treatment / by Dr. Laumonier ; tr. and ed. from the 2nd rev. and enl. French ed., by H.W. Syers. Source: Wellcome Collection.
Provider: This material has been provided by the Francis A. Countway Library of Medicine, through the Medical Heritage Library. The original may be consulted at the Francis A. Countway Library of Medicine, Harvard Medical School.
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![Trillat for the ability to manufacture the preparation. Commercial solutions of formol are of 40 per cent, strength. Formol possesses a very irritating odour : it is soluble in water; it coagulates albumin and hardens the tissues. When the solution is concentrated formol undergoes polymerisation and yields triformol, or trioxymethylene (CH-0)^, which possesses the same properties, and which can be easily obtained as a white powder, insoluble in cold water but soluble in warm water, by allowing the commercial solution of formol to evaporate. The experiments of Trillat, Berlioz, Aronsohn and Schmitt have proved that formol is inhibitory to the growth of pathogenic bacteria in quantity of 0 grm. '05 in 1,000, so that it stands almost on a level with corrosive sublimate. Unfortunately its microbicide power seems to be much less marked, inasmuch as Berlioz and Schmitt have shown that 1 in 1,000 solutions only kill pathogenic bacteria in six hours, and that the 1 per cent, solutions require not less than ten minutes for the same pur- pose to be effected. But the latter solution is too strong to be tolerated by the tissues. The considerable dispro- portion between the disinfecting power, the microbicide influence, and the irritating and caustic properties of formol specially stamp this product as very well adapted for the disinfection of instruments, clothing, &c., and this still more markedly as the va]30ur of formol is extremely bactericidal and its pressure allows of its penetrating very rapidly (two to four hours) everything contained in a dwelling-house. According to Trillat and Berlioz, Buck and Vander- linden, the toxicity of formol is 0 grm. '07 per kilogramme in the dog and 0 grm. '09 in the rabbit when given by intravenous injection, and 0 grm. '8 when given](https://iiif.wellcomecollection.org/image/b21172353_0336.jp2/full/800%2C/0/default.jpg)
