Licence: In copyright
Credit: The plant alkaloids / by Thomas Anderson Henry. Source: Wellcome Collection.
Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.
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![These two substances have the following formulse : CH CH II II CH. ,a CH CH NH Indolf. CH NH Skatole {l3»methylindole) ALKALOID OF ERYTHRINA HYPAPHORUS The seeds of this plant, which is grown as a shade tree in Java, were examined by Gieshoif ^ and found to contain a crystalline alkaloid, hypaphorine, which has been further examined by van Romburgh and Barger.^ Hypaphorine, C14H18O2N2, crystallises with IH2O, m.p. 255°, [a][, -f 91° to + 93°, and yields a sparingly soluble nitrate, m.p. 215°-220°. When heated with aqueous potassium hydroxide it yields trimethylamine and indole. When trytophan (/3-indole-a-aminopropionic acid) is methy- lated with methyl alcohol in presence of sodium hydroxide, and the resulting product heated at 100° for a few minutes with dilute sodium hydroxide solution, hypaphorine is formed. The latter is regarded therefore as a-trimethyl-/3-indolepropiobetaine. For other alkaloids containing a pyrrole or reduced pyrrole nucleus, see under carrot leaves (p. 398), coca (p. 108), tobacco (p. 39). * Meded. uit 's Lands Plant. 1890, 7, 29- ^ Proc. K. Akad. JVeten. Amst. 1911, 13,1177 ; Trans. Chem. Soc. 1911, 99, 2068.](https://iiif.wellcomecollection.org/image/b2196189x_0027.jp2/full/800%2C/0/default.jpg)
