Anti-choleraic inoculations in India / by W.M. Haffkine.
- Haffkine W. M. (Waldemar Mordecai Wolffe), 1860-1930.
- Date:
- [1895?]
Licence: Public Domain Mark
Credit: Anti-choleraic inoculations in India / by W.M. Haffkine. Source: Wellcome Collection.
Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.
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![it at the required state, it is necessary to pass it constantly through animals, in the same way as a vaccine lymph must be always taken fresh from a calf or a child, if one wants to have it at its full power. It is suflS.cient to say that, when I came from Calcutta to Agra for the first time, I was able to procure and to bring with me only six of the required animals. The most essentia] part of my method, which forms its distinguishing feature, could be carried out, during the whole time of my nomadic operations in the country in a most unsatisfactory manner. It must not be forgotten that, from the com- mencement, I announced that the protection which I hoped to obtain was not yet established as certain, and the operations, which I was about to perform, constituted an attempt or trial in that direction. I could only offer the possibility of protection and an assurance of narmlessness, an oflfer which could not be a great inducement for many to subject them- selves to discomfort and temporary illness and loss of time connected with the operation. Be- fore the first observations have been made in a cholera place and the fear of the operation dis- sipated, I was obliged to content myself with inoculations producing only slight effect, a low degree of fever, and which in many cases left the subjects without any marked reaction at all. In the experimental inocualtions which had been done in Europe, in France and England, a dose of ^ of a culture tube has been used for each adult person. In the first inoculations in Agra I reduced the dose to only f of that amount, i.e., to j\ of a tube. Two accidents, which in them- selves had nothing to do with the operation, attended the first inoculations, and the whole](https://iiif.wellcomecollection.org/image/b21689982_0015.jp2/full/800%2C/0/default.jpg)
