Volume 2

Final report of the Royal Commission appointed to inquire into the relations of human and animal tuberculosis.

  • Great Britain. Royal Commission on Tuberculosis
Date:
1911
Catalogue details

Licence: Public Domain Mark

Credit: Final report of the Royal Commission appointed to inquire into the relations of human and animal tuberculosis. Source: Wellcome Collection.

    54/566 (page 52)
    EXPERIMENTS MADE TO ASCERTAIN WHETHER TUBERCLE BACILLI WERE PRESENT IN APPARENTLY NORMAL TISSUES OF SWINE ONE OR MORE MONTHS AFTER Number Les or Leys Duration Tissue used of Dose eae Uenas of of for Guinea-pig | Result in Guinea-pig. esate isease In Swine. | Hxperiment.| Inoculation. 18 5°58 cc. of tuberculous | Very slight genera- | 39 days Spleen No tuberculosis. milk estimated to con- lised T. tain one million T.B. rf Spleen Slight tuberculosis. 34 7-05 ce. of milk estimated | Local T., and one or 46 days | to contain five million two disseminated \ Kidney No tuberculosis, TB, | lesions. Left bronchial | General tuberculosis. 96 55°85 cc. of milk estimated | G. T. moderately 37 days | gland. j to contain ten million severe. Kidney - No tuberculosis. T.B. 40 | 141 cc. of tuberculous Local T. only 45 days Spleen . No tuberculosis. milk estimated to con- tain ten million T.B. 38 5°58 ce. of milk estimated | Very slight genera- 109 days Spleen No tuberculosis, to contain one million lised T, 1B: 36 27°94 cc. of milk estimated | G.T.,notvery severe 115 days Liver No tuberculosis. to contain five million Lung No tuberculosis, 14 1°36 cc. of milk estimated | Slight T. of neck 42 days to contain 100,000 T.B. glands, and one Spleen No tuberculosis. or two dissemi- nated lesions. 64 13°6 cc. of milk estimated | Slight T. of ileo- 42 days Kidney No tuberculosis, to contain one million colic glands only. TB, 66 18°6 cc. of milk estimated | Slight T. of ileo- 90 days Spleen No tuberculosis, to contain one million colic glands, and T.B. one or two dis- seminated lesions. Result of Inoculation of Tissues into Guinea-pigs, Number Duration wo 2 _3 Virus. Dose. and Age of of iis Eo aa Animal, |Experiment}| as | =% c a as o d5 | 3a] & FA an ek Nee 3 Sieh BS food a hebvelare aa ee S ae a a A 4a 3) aa) Q a PIGS. 7 pp 92775 | ( 50°0 mg. daily 141 K. 7 days} + + + — —_ — — se A Ae |) for two days. | (8 weeks.) from Lupus.) Do. 143 K.13 days| + ne ai ht ils eh. (8 weeks.) H. 104, “E.R.” 377°0 mg. 123 K. 5 days om — ee (Human.) (16 weeks). | 500 mg. 105 K, 2 days + _ _ _ = H. Me Be | | (123 weeks). ] 50°0 mg. 103 K, 4 days | =u 4+ ole + Ub le eee (123 weeks). ( 75°0cc.of emul- 125 K, 7 days} + + ~~ _ _— —_ — — x | sion of G.P’s, | (12 weeks). H.67, E.P.’.3. |} organs (T.B, (Human.) numerous), | L Do. 127 K.12 days} + | + — — eae os ag fe (12 weeks). '( 100-0 mg. 149 KOT dayeivetee dias, 1 Gir | ie ae H. 14 ‘ (11 weeks). | | { 100°0 mg, 151 K, 7days] + + + = -- ; (11 weeks),