A system of medicine / by many writers.

Date:: 1911

Credit: A system of medicine / by many writers. Source: Wellcome Collection.

Provider: This material has been provided by UCL Library Services. The original may be consulted at UCL (University College London)

119/944 page 95

$ix. — 37. OsLER. Am. Jowrn. Med. aSc-., Pliila., 1888, xcv. 632.-38. Idem. Brit. Jimrn. Dermat., 1900, xii. 227. — 39. Idem. Princijjles of Medicine, 1909, 1110.— 40. Paget, J. Med. Times and Gaz., 1864, i. 331.—41. Parsons. Lesions of the Trif,'emiual Nerv^e, Lancet, London, 1907, i. 1413.—42, Polland. Zentralhl. f. iuiirrc Med., Leipzig, 1907, xxviii. 41 et scg. —43, Pospelow. Arch. f. Dermat. u. Siijih., Wien, 1898, xliv. 91.—44, Quincke. 3fonatssh. f. 2)raf-'t. Dermat., Hamb. 11. Leipz., 1882, i. 129.—45. Raynaud. Quoted by Monro, Raj'uaud's Disease, (ll is^row, 1899, 81.—46. Riedel. Arch. f. klin. Chir., Berlin, 1906, Ixxxi. 202.— 47. Idem. Ibid., 1894, xlvii. 216.—48. Rochet. Semaine m6d., Paris, 1892, xii. 35. - 19. RoLLESTON. Lancet, London, ]902, ii. 805.—50. Rose, Felix. Nouv. icon. Ja Salpet., Paris, 1908, xxi. 64—51. Russell, A. E. Clin. Journ., London, 1908, wxii, 136,—52. Samuel. Virchovjs Arch., 1890, cxxi. 404.—53. Idem. Dietrophischen rren, Leijizig, 1860.—54. Schlesinoer. Die Syringomyelie, Leipzig, 1902. — 55. Starling. Schdfers Textbook of Physiology, 1898, i.. Art. Lymph. — 56. Steven, J. L, Glasgoiv Med. Journ., 1898, xlix. 258.—57. Idem. Internat. Clin., Phila., 1897-8, 7 ser,, ii. 195.—58. Weir Mitchell. Gunshot Wounds and other Injuries of Nerves, Philadelphia (out of print). — 59. Idem. Injuries of Nerves and their Consequences, Phila., 1872. 157.—60. VuLPlAN. Legons sur i'ajJjyareil vasomoteur, 1875, tome ii. Neurotrophic Affections of Bones and Joints Introductory.—The conception of trophic centres which control the nutrition of the l>ones and joints was formulated b}' J. K. Mitchell, as far back as 1831, in an article on the occurrence of arthropathies as sequels of disease or injury of the spine. Mitchell even suggested that the articular lesions in rheumatic fever might be due to changes in the nervous system. Although these hypotheses did not meet with general acceptance at the time, their influence is shewn l)y occasional records during the next thirty years of arthropathies following various aftections iof the brain and s[)inal coid. But it was not till 1868 that Charcot I described the trophic lesions of tabes dorsalis, the first case in this country ibeing reported by Sir Clifford Allbutt in the following year. Charcot's observations established once for all the existence of the joint disease which bears his name, and on Avhich such a large part of our knowledge of nervous artln'oi)athies dej^ends. Plis work, indeed, was so complete 'that little remained for subsequent observers except to offer explanations, jand to fill in details. The power of his name at once secured him a respectful hearing, and, in France at all events, a ready acquiescence; but elsewhere, particularly in Germany, his views met with most strenuous opposition, which indeed is not even yet silenced. A^irchow, Volkmann, and Striirnpell contested his deductions ; and so great was their influence that, for ten or fifteen years after, while records of Charcot's disease were numerous in France and fairly common in England, in Germany their scarcity was remarkable. Weir Mitchell's description of spontaneous fractiu'es in tabes, in 1873, foimed an addition to our knowledge of hardly less importance than Charcot's of 1868. This was followed at a wevy short interval by further observations from Charcot, who early saw the intimate relation between the changes in the bones underlying spontaneous fracture and those which$

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