Pemphigus of the skin and mucous membrane of the mouth, associated with "essential shrinking" and pemphigus of the conjunctivae / by A. Hill Griffith.

  • Malcolm Morris
Date:
[1889]
Catalogue details

Licence: Public Domain Mark

Credit: Pemphigus of the skin and mucous membrane of the mouth, associated with "essential shrinking" and pemphigus of the conjunctivae / by A. Hill Griffith. Source: Wellcome Collection.

Provider: This material has been provided by UCL Library Services. The original may be consulted at UCL (University College London)

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    congested, and the cornea is nearly opaque. The iris is muddy and the pupil rigid. Vision is nearly lost, but the percep- tion of light remains. Movements of the globe are restricted in the following directions—outwards, upwards, and downwards. The right eye.—This is not so badly affected as the left. There is some shrinking of the lower cul-de-sac. The cornea is clear. The pupil reacts to light and during accommodation. Vision is limited to large type at near distances. No bull® or vesicles are visible on any part of the skin, mucous membrane, or conjunctivae. Progress of the case. November 26th.—The remains of a recent bulla exists on the right temple. On the skin of the lower lip is a clear vesicle, about 3 mm. broad. On the mucous membrane of that lip, of the floor of the mouth, and of the hard palate, are a few unbroken vesicles. December 3rd.—She entered the hospital as an in-patient. The shrinking of the conjunctiva of the right eye has made con- siderable progress. January 1st, 1889.—The condition is about the same as on Dec. 3rd. There are no fresh vesicles, but the old vesicles still exist in the mouth, and are unbroken. The dysphonia is more marked, the patient speaking in whispers. Jan. 4th.—An unbroken vesicle was seen on the lower part of the conjunctiva bulbi of left eye. Feb. 28th.—Fresh bullae have formed, one on the front of the neck, two others on the mucous membrane of the lower lip. At the outer angle of right eye the conjunctiva has shrunk into narrow bands, which pass in a vertical direction from one lid to another (see plate, in which the right eye has been drawn separately). The cilise of both lids are curved inwards, and brush against the cornea and the sclerotic conjunctiva. On the right eye only a few cilia) of upper lid at the inner angle are misdirected, the remaining ones being normal. March 10th.—Fresh vesicles continue to make their appear- ance upon the mucous membranes of the lower lip and the floor of the mouth. Eemarks.—We have collected and arranged in the form of a table all the cases of pemphigus conjunctivae, which have been published up to the present time. We have chosen this V 2
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