Observations on the history, pathology, and treatment of cancerous diseases / by Oliver Pemberton.

Date:
1858
Catalogue details

Licence: Public Domain Mark

Credit: Observations on the history, pathology, and treatment of cancerous diseases / by Oliver Pemberton. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

    48/96 page 26
    being unsuspected. Dissection : melanotic deposits, in lungs, on pleura, in heart, pericardium, beneath mucous membrane of bronchi; in serous membranes of abdomen, liver, spleen, kidneys. The deposit in the liver was partly white, and of a cerebriform character; also in the clavicle-rib and internal table of the skull.—Trans. Med. Chir. Soc. of Edinburgh ; vol. i, p. 271. Duration: from extirpation until death, “ten months.” Case 4. A man, cetat 30, under the care of Mr. Wilson, at Man- chester, January 30th, 1824. The left eye. Treatment, by extirpation, April 19th. Dissection : deposits, cellular membrane of trunk, in liver, pancreas, spleen, kidneys, peritoneum, pleurae, lungs. There was no return in the orbit.—Fawdington: case of melanosis. London, 1826, 8vo. Duration: a, from first appearance to operation, “nine months;” /3, from operation until death, “ six months and a half.” Case 5. A man, cetat 29, a black, a native of Madagascar, under the care of Mr. A. Montgomery, in the Civil Government Hospital, Mauritius, July 8tli, 1827. A small sore on the side of the left foot, formed eighteen months prior to his admission. This became a rough tuberculated growth resembling a cauliflower, of a deep livid colour, approaching to blue. Numerous mulberry tubercles about feet. Enlarge- ment, generally, of glands, passing upwards towards groin, where they were much increased, and formed a considerable tumour. August 6th. Treatment, by amputation below knee. The stump healed. Two months subsequently the gland in the groin sloughed, and numerous tubercles formed in the trunk and limbs beneath the skin. Died 23rd January, 1828. Dissection: the tumour in groin of a brain- like character, intermingled with massess of black pigment. Black tubercles in cellular membrane of pleura and peritonaeum. In the liver. The heart’s surface was completely covered by them, and its structure so completely changed, as to be scarcely recognised. The left lung was also melanotic.—Lancet, vol. ii, 1844; p. 280. Duration: a, from first appearance to operation, “nineteen months;” p; operation until death, “ five months and a half.” Case 6. A male, cetat 46 ; a merchant’s clerk; in the Hospital Beaujon, March 28th, 1829. The primary disease was situated on the palm and back of the hand. It had appeared as a blackish stain, like an ecchymosis, without known cause, seven or eight years previously, and had made scarce any progress for a year. The growth was then destroyed by caustic, and the application was renewed from time to time up to 1828. Severe lancinating pains were latterly experienced. By the application of an arsenical paste, the wound healed; but a tumour of a similar character appeared on the back of the hand, in the fii’st inter-osseous space, and in a little while the first seat of the disease again ulcerated. Pain was again marked, .and finally the hand was amputated, and he was discharged well in April, 1829.
    digitised image 1
    digitised image 2
    digitised image 3