The physiology of the amino acids / by Frank P. Underhill.

  • Frank Pell Underhill
Date:
1915
Catalogue details

Licence: In copyright

Credit: The physiology of the amino acids / by Frank P. Underhill. Source: Wellcome Collection.

    124/210 (page 102)
    R.CH2.C(OH) .nh2.cooh Hydroxy-amino acid R. CH2. CO. COOH + C02 + NH3 Ketone acid By cleavage of C02 this becomes a fatty acid with less carbon atoms. R. CH2. CO. COOH — C02 = R. CH2. COOH Ketone acid By further cleavage this fatty acid is changed to C02 -j- H20. In an abnormal organism, such as that of the dia- betic, leucine may yield beta-oxybutyric acid instead of acetone. The reactions involved follow. CH3CH3 CH3CH3 CH3CH3 CHS \/ \/ \/ 1 CH CH CH CHOH CH2 CH2 CH2 CH2 CH.NH2 CHOH COOH COOH COOH COOH Leucine Oxy-isobutyl Isovaleric /S-oxy-butyric acetic acid acid acid