Epidemic infantile paralysis (Heine-Medin disease) / Tr. by H. Ridley Prentice.

  • Römer, Paul Heinrich, 1876-
Date:
1913
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Licence: Public Domain Mark

Credit: Epidemic infantile paralysis (Heine-Medin disease) / Tr. by H. Ridley Prentice. Source: Wellcome Collection.

Provider: This material has been provided by the Augustus C. Long Health Sciences Library at Columbia University and Columbia University Libraries/Information Services, through the Medical Heritage Library. The original may be consulted at the the Augustus C. Long Health Sciences Library at Columbia University and Columbia University.

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    Contents. Chapter I. The Development of our Knowledge of the Nature of the Disease of Heine and Medin. Nomenclature, p. i—Historical Retrospect, p. 3. Chapter II. The Symptomatology of the Disease in Man. PAGE I.—Historical 6 The period before Heine, 6—Heine's work, 7—From Heine to Medin, 10—Medin to Wickman, 13. II.—The Symptomatology in Man 13 Period of incubation, 13—Prodromal symptoms, 13—Stage of paralysis, 14 (Abortive type, 14; Spinal types, 15; Type simulating Landry's disease, 17; Bulbar and Pontine types, 18; Cerebral type, 18; Ataxic type, iq; Polyneuritic type, 19; Aleningitic type, 19)—Prognosis, ig—Sporadic infantile paralysis, 20. Chapter III. Etiology of the Disease. I.—Microscopical and Cultural Researches with Experiments on Animals 22 The older views, 22—Strumpell's hypothesis, 23—The era of cocci, 24-—The accumulation of negative results, 25—Per- sonal bacteriological research, 26—Important microscopical findings, 27—Specific intracellular bodies, 29— Cultures of the virus,' 29—Experiments on animals, 30. II.—Experimental Research ox Poliomyelitis in Monkeys— Clinical History of Experimental Poliomyelitis 31 Landsteiner's original experiment, 31—Personal experiments with monkeys, 32 [a] Source of the virus used in my experiments ... ... 34 Susceptibility of monkeys to the virus of poliomyelitis, 42. (b) The clinical history of poliomyelitis in monkeys ... ... 43 Period of incubation, 43—Prodromal symptoms, 44— Stage of paralysis, 45 ((a) Poliomyelitis acutissima, 46; (b) Poliomyelitis acuta, 47; [c) Typical spinal para- lysis, 47; (d) Bulbar and Cerebral forms, 49; (e) Gastro-intestinal symptoms, 54; (/) Abortive forms, 54; (g) Marasmic forms, 56; (h) Recovery from the acute stage, 57; (i) Recovery from the paralysis, S7', (k) Relapses, 59)—Prognosis, 60.