Researches into the antagonism of medicines : being the report of the Edinburgh Committee of the British Medical Association / by John Hughes Bennett, chairman and reporter.

  • British Medical Association. Edinburgh Committee.
Date:
1875
Catalogue details

Licence: Public Domain Mark

Credit: Researches into the antagonism of medicines : being the report of the Edinburgh Committee of the British Medical Association / by John Hughes Bennett, chairman and reporter. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    out of its mouth. The cat defecated and micturated several times. Forty minutes later, it continued in much the same condition. Saliva- • tion was profuse. Animal suffered from tenesmus, and it had a con- stant straining from the bowel of a clear fluid, like mucus. The limbs, especially the posterior ones, were much weakened, but the animal could still run with difficulty. It could not jump; it made attempts to do so over a bench about two feet high, but failed. The breathing Table LI.—Experiments with Caffeine. . of Kx- rimont. ■^1 to <^ O General Effects. Result. Post Mortem Examination. o o ^ !=• P ^ Frog l-128th Very slight weakness of posterior extremities. Recoveiy 435 Frog - Slight weakness of poste- Kecovery rior extremities. 436 Frog Considerable weakness of Recovery luuhs; respii'ation im- paired ; reflex action di- minished. 437 Frog i-ieth Almostcomplete paralysis; reaph-ation stopped; al- most complete loss of re- flex action ; prostration; cutaneous sui-face con- gested. Recovery 438 Frog l-12tli Complete prostration; re- spiration stopped; reflex action lost j under siu-face of skin, tongue, & mouth, congested; stasis of blood in capillaries. Death Heart beat feebly; great congestion of viscera. When brain was irritat- ed.muscles of face contracted; on iiTi- tating spinal cord, nei'ves ormuscles, there were muscu- 439 rrog lar contractions. liigature of femoral artery; symptoms same as No. Death Same as No. 438; no difference be- 438; no difference be- tween the two logs tween the two limbs. 4t0 Frog I-10th Spinal cord exposodduring life ; sjTnptoms the same as No. .1.38, On touchin*' anterior or posterior co- lumns with ])oint of nee- dle, strong muscular con- tractions followed. After caffeine was injected, no contractions followed on touching the posterior co- Inmn, while anterior co- Death Same as No. 438. 411 Frog lumn remained an before. l-8th Prostration and loss of re- Death Same as No. 438. flex action; congestion of skin ; stoppage of respir- 443 Frog ation. l-3rd Rapid prostration and loss or rellox action, with Death Samo'as No. 438. 413 Frog nsnnl symptoms. 1 fjitraturciof fcmoml arloiy; very nijiid pi'DStralioii & lo.is of rellex action; no (liffcrcnce between the two limbM. Dciilh Same No. 'IBS. No difTcroMcn between the two lejis.