The 'Oriental sore,' as observed in India : a report / by T.R. Lewis and D.D. Cunningham.

  • Lewis, T. R. (Timothy Richards), 1841-1886.
Date:
1877
Catalogue details

Licence: Public Domain Mark

Credit: The 'Oriental sore,' as observed in India : a report / by T.R. Lewis and D.D. Cunningham. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    [ ] in the liair arid sebaceous follicles in Lupus find their counter- part in our own description of this sore, and we are particularly struck with the similarity which exists between his description of the epidermoid character of some of the portions of dsieased tissue in Lupus and what we have seen in the Oriental sore, and that, too, at a considerable distance from the epi- thelial layers. Professor Virchow writes : The Lupus growth consists of young, tough, and generally, vas- Jt^oi:^yV^:^:Z ° '^^ ^ular, granulating tissue, which as a rule contains small round cells, which may so closely resemble the cells of the rete Malpighii, that it is difficult to differentiate the boundaries between the rete and the Lupus tissue. Frequently it seems as though the boundary had been obliterated, but I cannot admit, what might readily be supposed, that the cutis itself becomes transformed into a rete Malpighii, or that the elements of the rete press into the cutis. A decidedly epidermoid charac- ter is not assumed by the cells : they are young cells, of ir- regular form and of moderate durability. * * * The cells do not lie loose in the areolae, but are surrounded by a tough, mucous intercellular substance giving a precipitate with acetic acid. The cells are delicate and fragile, and one may readily infer that they are only nuclei. * * * A careful examination, however, will reveal that they are cell bodies, generally rounded, but often oval or even spindle-shaped. They envelope the round or oval, large and generally single nucleus tolerably closely, and the latter is provided with one or two nucleoli. It is only towards the surface that the cells become multi-nucleated, occasionally presenting precisely the appearance of pus corpuscles.* Subsequent to the period at which this description was written several distinguished observers Thoma.Lange.&c, on Lupus. , . , . i ,. - j.i have paid special attention to the pathology of Lupus, and notably so during the present and past year. Thoma also directs attention to the gradual extinction of the boundary line between the corium and rete Malpighii—such an extinction as may be observed delineated in our figure of a section of the Oriental sore (Fig. 7, c) ; and lays stress on the point that the cell formations which take place in the corium are the essentially Lupus elements. At * Op. cit., ptigcs 487-8.