Observations on box (buxus sempervirens), with especial reference to the true nature of tetanus / by Sydney Ringer and William Murrell.

  • Sydney Ringer
Date:
1876
Catalogue details

Licence: Public Domain Mark

Credit: Observations on box (buxus sempervirens), with especial reference to the true nature of tetanus / by Sydney Ringer and William Murrell. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

    17/34 page 15
    Table showing condition of sciatic nerves in frogs poisoned by box after ligature of one of the iliacs. No. of experi- ment. Date. Weight of frog. Vessels tied. Grns. in- jected Relation of dose to weight of animal. Time of observation after injection. No. of com- parative obser- vations . Result. 1876. Grms. I Ap. 12 34 R. iliac 9 1 h. 41 m ? No difl'erenee II „ 12 30 if 5 Hh. ? III „ 25 65 a 27 • . • lh. 2 if 1 h. 5 m. 2 if 1 h. 10 m. 3 if 1 h, 15 m. 1 1 li. 20 m. 3 a 1 h. 30 m. 1 a 1 h. 45 m. 3 a 2 h. 1 2h. 30 m. 3 2 h. 45 m. 1 a 3 h. 10 m. 2 a 3 h. 30 m. 1 a 4h. 1 a 4 h. 10 m. 1 IV » 26 25 9 ... 9h. 40 m. 13 y May 2 24 a 12 ... 4h. Many The right sciatic nerve conducts better than the left, although the difference is slight 5h. 7 The right nerve still acts better than the left VI 2 25 12 , , , 6h. 6 No difference VII „ 2 22 a 12 • •• 2h. 10 )) VIII „ 2 19 i> 9 ... lh. 8 19 In one instance there was a decided difference in the excitability of the two sciatics, the nerve of the protected limb acting distinctly more energetically than that of the other. What value are we to attach to this exceptional result ? In answer to this question we cannot do better than detail another experiment in which the operation for ligature of the iliac artery was performed. The box was given as usual, and immediately after the decline of the tetanus and the occurrence of complete paralysis the
    digitised image 1
    digitised image 2
    digitised image 3