Contributions to the morbid anatomy of chronic inflammation of the mucous membrane of the uterus (endometritis corporis chronica) / by Leopold Meyer.

  • Meyer, Leopold, 1852-1918.
Date:
1887
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Licence: Public Domain Mark

Credit: Contributions to the morbid anatomy of chronic inflammation of the mucous membrane of the uterus (endometritis corporis chronica) / by Leopold Meyer. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    often provided with a nucleolus, 7-15/“ long, 5-10/i broad, and small, highly-stained ones, oval or spindle-shaped, the oval ones’ diameter being 3.7-6 that of the spindle-shaped 7-8 /“ long, 3-4 broad. The investigations, the results of which are given in this paper, have been made by me on parts of the uterine mucous membrane, scraped ofl' by aid of Sims’ Curette, and then laid as quickly as possible in absolute alcohol. They are then imbedded in Celloidin, the sections stained with Hmmatoxylin, with Hmmatoxylin and Eosin, with Lithion-picro-car- mine, and Bismark brown, and they were then examined, either in glyc- erine or Canada-balsam-xylol. The patients on whom the curettings of the mucous membrane were performed suffered from severe metrorrha- gia or menorrhagia. In one patient only was there a chronic catarrh, with considerable discharge, but no hemonhage, The interglandular tissue is generally seen formed by closely packed cells, so that the basal substance properly so-called, the stroma, is not visible, not even in very thin sections. Where the stroma is distinctly visible, it appears almost always structureless, with an irregular, delicate delineation, perhaps produced by the influence of the alcohol. But I never saw anything resembling that described by Lleinricius: a net of meshes formed by star-formed cells with thin processes that anastomose among each other. It seems evident from H.'s description that it is his opinion that this net of meshes is not a morbid inflammatory product, but that it is present in the normal uterine mucous membrane. But neither here have 1 I been able to find anything corresponding to this reticular tissue. Of j course it is much more difficult to get fresh norinal uterine mucous mem- | brane for investigation than pathological, and I have only had two nor- | mal specimens at my disposal, both of which were procured 6-S hours | after death. The one patient had given birth to five children, the last ] time one-half year ago, and was still suckling. She died very suddenly j of Ursemia. The other patient, a girl fifteen years old, died of acute \ miliary tuberculosis during a catamenial period. The specimen from this ^ patient was first treated with Muller’s fluid and then with alcohol; the ; other specimen was immediately laid in absolute alcohol. The sections were stained and examined as above described. Notwithstanding a very ^ careful examination, — also by aid of immersion, as H. recommends, — I > did not, however, succeed in finding the net of meshes in these two speci- ^ mens, nor do any other investigators mention it. In the not-menstruated patient the body of the mucous membrane is formed of cells so close to- • gether that no basal substance is to be seen, nor can the borders of the \ single cells be distinctly observed, notwithstanding several different j methods of preparation, nuclei only., side by side, are visible. Most of /