Contributions to the morbid anatomy of chronic inflammation of the mucous membrane of the uterus (endometritis corporis chronica) / by Leopold Meyer.

  • Meyer, Leopold, 1852-1918.
Date:
1887
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Licence: Public Domain Mark

Credit: Contributions to the morbid anatomy of chronic inflammation of the mucous membrane of the uterus (endometritis corporis chronica) / by Leopold Meyer. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    we neither dare bring under the one kind nor the other, form often the chief mass of the interglandular tissue. This is the case in both of the following patients : — IV. Twenty-nine years old, single, one birth six years ago. Se- vere metrorrhagia during the last months, especially during the last six weeks. The mucous membrane, in part, in adenomatous degeneration. In other parts of it many vessels, chiefly small arteries. The interglandu- lar tissue is composed of closely-packed nuclei (protoplasm not distinctly visible) ; they were spindle-shaped, 7.3-14.7 long (mostly 8.8), 1.5-2.9 broad (mostly 2.3). They were but slightly stained, were somewhat granular. However, there were also smaller nuclei, both round and spindle-shaped, which were deeply stained, but there was a decisive majority of the former ones. V. Forty-six years of age ; nine births and four miscarriages ; her last child was born nine months ago, and since frequent hgemoiThages. The glands somewhat more numerous, expanded, and twisted than in normal state. Enormous quantity of vessels, chiefly arteries of middle size. The borders of the cells indistinct. There were dark small nuclei (44/“; 3.7 /“) and larger oval, slightly-stained nuclei (7.3 : 6.0 i“) ; but most of the nuclei are between these two with respect to their size, form, and appearance. I have mentioned that we often find spindle-shaped cells, — cells resem- bling those of connective tissue, and that they are chiefly found surrounding the glands. They can, however, also appear elsewhere in the tissue. We sometimes even find them in bi'oad bands, although I never saw this so exquisitely developed as it seems to have been in the cases which Schroder] describes bv the name of Endometritis dysmenon’hoica. We find in some patients gradual transitions from the common cells with the round nuclei to the spindle-shaped cells ; in others, transitions from the small spindle-shaped cells with dark nuclei to large spindle-shaped cells with granular protoplasm and oval, slightly granular, light nucleus. Such gradatory cells may be seen in Fig. 2. We often find in the inter- glandular ti.ssue cells whose nuclei are dividing or have already divided. I am unable to decide whether these cells are immigrated lymphoid cells (pus cells), or whether they are the cells originally present in the mucous membrane. But we often see the tissue infiltrated wdth quantities of small, round, very deeply-stained nuclei whose diameter is 3-4With- out any doubt these are immigrated lymphoid cells, and in one case I saw them gather in small, round heaps immediately under the epithelium, /.c., tormins: small abscesses, about o 2 ™'- in diameter. o 1 L. cit.