Observations on the remarkable effects of iodine in bronchocele and schrophula : being a translation of three memoirs published by I.R. Coindet, M.D. of Geneva.

  • Jean-Francois Coindet
Date:
1821
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Licence: Public Domain Mark

Credit: Observations on the remarkable effects of iodine in bronchocele and schrophula : being a translation of three memoirs published by I.R. Coindet, M.D. of Geneva. Source: Wellcome Collection.

Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.

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    • The solution of this suit, in a sufficient quantity of water, may take up still more iodine, and thus form an ioduretted hydriodate of potass, a peculiarity of which I have availed myself to increase the force of the remedy in those cases where a goitre of hard consistence, great bulk, or long duration, would seem to resist the action of the simple saline solution; in this way I have often obtained the most remarkable cures. Iodine will dissolve in a certain proportion in ether and spirits of wine. Gay Lussac found that water dissolves 1-7,000th its weight. One ounce of spirits of wine at 35° of concentra- tion, dissolves at 15° of Reaumur, (67° Fahrenheit) and under the ordinary pressure, 60 grains of iodine, or about one-ninth part of its weight; at 40° of con- centration, and under the same condition, it dissolves 84 grains, or about one-sixth, from whence it appears the spirit of wine dissolves more or less according to its strength. To avoid all error in the dose in this third prepa- ration, which I employ under the name of tincture of iodine, I am in the habit of prescribing 48 grains of iodine, to one ounce of spirits of wine at 35°. , This preparation I have employed more frequently than the preceding, (perhaps with greater success) on account of its being easily prepared in places where we cannot always find apothecaries sufficiently instructed to obtain pure saline kydriodates, deeming it the principal object of my researches, to be assured of the effect of a remedy I am anxious may pass into general use. The tincture should not be prepared long before its use, since it gives place to a crystalline deposit of iodine ; besides, from the great quantity of hydrogen the alcohol contains, and its great affinity for iodine, it is speedily converted into ioduretted hydriodic acid. ; This is doubtless an exceedingly active remedy, but as there are, in certain cases, reasons for pre- 19
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