Chemistry of urine : a practical guide to the analytical examination of diabetic albuminous, and gouty urine / Alfred H. Allen.
- Alfred Henry Allen
- Date:
- 1895
Licence: Public Domain Mark
Credit: Chemistry of urine : a practical guide to the analytical examination of diabetic albuminous, and gouty urine / Alfred H. Allen. Source: Wellcome Collection.
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![the cupric oxide reducing power being 98'8, compared with glucose as 100. On distillation with hydro- chloric acid, glycuronic anhydride (as also uro-chloralic acid) yields furfuraldehyde, a trace of which substance is also obtainable on similarly treating normal urine. Glycuronic acid itself is dextro-rotatory ([a]u = -f 35°), but many of its compounds are Igevo-rotatory.^ It reduces Fehling’s solution on heating, and precipitates the metals from hot alkaline solutions of silver, mercury, and bismuth. On oxidation, glycuronic acid yields camphoric and formic acids. By treatment with bromine it yields saccharic acid, CgH^^oOs’ ^ reaction which in- dicates the presence of an aldehyde group and the close relation between glycuronic acid and dextrose. Saccharic acid can again be reduced to glycuronic acid by treatment with sodium amalgam, further treatment yielding gulonic acid, CgH;^2075 ^ body which does not reduce Fehling’s solution. (Fischer and Piloty, Ber., xxiv. 521 ; Jour. Cliem. Soc., lx. 667.) When boiled with caustic alkali, glycuronic acid yields oxalic acid as an invariable product. Catechol and protocatechuic acid are also formed if concentrated alkali be employed for the treatment. Glycuronic acid is distinguished from glucose by not undergoing the alcoholic fermentation when treated with yeast. On the other hand, when fermented in presence of cheese and chalk it yields lactic and acetic acids. Glycuronic acid forms a potassium salt which crystallises in needles. The sodium salt is similar. The zinc, cadmium, copper, silver, and calcium salts are uncrystallisable. The barium salt is amorphous ^ After taking chloral hydrate the urine contains trichlorethyl-glycuronic acid (“uro-chloralic acid”), a Iffivo-rotatory body which is decomposed into trichlorethyl alcohol and dextro-rotatory glycuronic acid.](https://iiif.wellcomecollection.org/image/b28138818_0058.jp2/full/800%2C/0/default.jpg)
